Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
A;B;C;D;G |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Canada |
Literature Information
PubMed PMID
|
15985011
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2005 |
Journal
|
Journal of viral hepatitis |
Title
|
Response to long-term lamivudine treatment (up to 5 years) in patients with severe chronic hepatitis B, role of genotype and drug resistance. |
Author
|
Moskovitz DN,Osiowy C,Giles E,Tomlinson G,Heathcote EJ |
Evidence
|
YMDD mutation at rtL180M and rtM204V/I measured by restriction digest of amplified products.
|
|
|