|
Mutation Information
|
Mutation Site
|
M552I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
33364535
|
|
Published Year
|
2020 |
|
Journal
|
AIMS microbiology |
|
Title
|
Mutations and methods of analysis of mutations in Hepatitis B virus. |
|
Author
|
Rajput MK |
|
Evidence
|
Assays with transiently transfected cells revealed an increasing lamivudine resistance from wild type strains to single mutated strains (L528M or M552V) to strains with the M552I mutation and to double mutated strains (L528M plus M552V or L528M plus L552I).
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HBV Mutation Detail Information