HBV Mutation Detail Information

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Mutation Information

Mutation Site	M250V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	entecavir (ETV)

Literature Information

PubMed PMID	18070286
Disease	Chronic hepatitis B
Published Year	2007
Journal	Journal of viral hepatitis
Title	Hepatitis B virus polymerase variants associated with entecavir drug resistance in treatment-naive patients.
Author	Jardi R,Rodriguez-Frias F,Schaper M,Ruiz G,Elefsiniotis I,Esteban R,Buti M
Evidence	The aim of this study was to determine the prevalence of HBV variants associated with ETV resistance (rtI169T, rtT184G, rtS202I, rtM250V) in naive patients before and during lamivudine therapy.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation