|
Mutation Information
|
Mutation Site
|
A194T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF) |
|
Country
|
Ghana |
Literature Information
|
PubMed PMID
|
20631103
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2010 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Detection of highly prevalent hepatitis B virus coinfection among HIV-seropositive persons in Ghana. |
|
Author
|
Geretti AM,Patel M,Sarfo FS,Chadwick D,Verheyen J,Fraune M,Garcia A,Phillips RO |
|
Evidence
|
The overall prevalence of major drug resistance mutations in RT was 4/86 (4.6%), comprising the lamivudine resistance mutations V173L, L180M, and M204V in three patients and the unusual combination of V173L plus the tenofovir resistance mutation A194T in the fourth patient.
|
|
|
HBV Mutation Detail Information