HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	Japan

Literature Information

PubMed PMID	22523569
Disease	Chronic hepatitis B
Published Year	2012
Journal	PloS one
Title	Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing.
Author	Nishijima N,Marusawa H,Ueda Y,Takahashi K,Nasu A,Osaki Y,Kou T,Yazumi S,Fujiwara T,Tsuchiya S,Shimizu K,Uemoto S,Chiba T
Evidence	The most commonly detected mutation was M204VI (9 cases) and M250VI (11 cases), which were resistant to lamivudine and entecavir, and entecavir, respectively. Other mutations resistant to adefovir were detected in 7 (50.0%) and 3 (21.4%) cases at A181TV and N236T, respectively (Table 4).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation