|
Mutation Information
|
Mutation Site
|
F221Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir dipivoxil (ADV) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
19578241
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Antiviral therapy |
|
Title
|
Adefovir dipivoxil resistance patterns in patients with lamivudine-resistant chronic hepatitis B. |
|
Author
|
Santantonio T,Fasano M,Durantel S,Barraud L,Heichen M,Guastadisegni A,Pastore G,Zoulim F |
|
Evidence
|
In one of the two patients with primary treatment failure, the following mutation pattern was observed before adding ADV:rtL180M, rtM204I/V, rtV173L, rtR138K, rtN139H,S219A, F221Y and rtL229F.
|
|
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HBV Mutation Detail Information