Mutation Information
Mutation Site
|
Q215P |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
D |
Relevant Drug
|
lamivudine (LAM);adefovir (ADV) |
Country
|
Korea |
Literature Information
PubMed PMID
|
24064642
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2013 |
Journal
|
Indian journal of medical microbiology |
Title
|
Mutation analysis of hepatitis B virus reverse transcriptase region among untreated chronically infected patients in Ahvaz city (South-West of Iran). |
Author
|
Hamidi-Fard M,Makvandi M,Samarbaf-Zadeh A,Hajiani E,Shayesteh A,Masjedizadeh A |
Evidence
|
The most frequent secondary resistance mutation was found at position rt215 (10 patients, 50%) which included rtQ215S mutation in 4 patients, rtQ215P mutation in 3 patients, rtQ215H mutation in 2 patients and rtQ215M mutation in 1 patient. The rtN238H mutation was detected in 2 (10%) patients.
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