HBV Mutation Detail Information

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Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.A181T+rt.N236T+s.C69*+rt.S78T;rt.A181T+rt.N236T+rt.A181V+s.C69*+rt.S78T;rt.N236T+rt.M204V+rt.A181T+rt.L180M+s.C69*+rt.S78T
Country China
Literature Information
PubMed PMID 31398372
Disease Chronic hepatitis B
Published Year 2019
Journal Antiviral research
Title Investigation of hepatitis B virus (HBV) rtS78T/sC69* mutation in a large cohort of chronic HBV-infected patients with nucleoside/nucleotide analogue treatment.
Author Luo D,Liu Y,Chen R,Niu M,Liu L,Li X,Li Q,Huang B,Wang J,Xu D,Lin S
Evidence The rtS78T/sC69*-containing mutants, including rtS78T/sC69*, rtS78T/sC69* + A181T, rtS78T/sC69* + N236T, and/or rtS78T/sC69* + A181T + N236T, were detected in various proportions during ETV therapy in samples B1, B2, and B3, and after the suspension of ETV therapy in sample B4 (Fig. 2B).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation