HBV Mutation Detail Information

> Q215S Search Result


Mutation Information
Mutation Site Q215S
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV)
Country Spain
Literature Information
PubMed PMID 18167643
Disease HBV-HIV coinfection
Published Year 2007
Journal Journal of acquired immune deficiency syndromes (1999)
Title Selection of hepatitis B virus (HBV) vaccine escape mutants in HBV-infected and HBV/HIV-coinfected patients failing antiretroviral drugs with anti-HBV activity.
Author Sheldon J,Ramos B,Garcia-Samaniego J,Rios P,Bartholomeusz A,Romero M,Locarnini S,Zoulim F,Soriano V
Evidence Of the 19 HBV-monoinfected patients treated with ADV, 2 harbored the rtN236T mutant and 5 harbored viruses with changes rtQ215S, rtI233V, and rtS213T + rtV214P, all of which have been associated occasionally with ADV resistance in HBV.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation