|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181V;rt.M204I+rt.M204V+rt.N236T+rt.A181V |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24710668
|
|
Disease
|
HBV infection
|
|
Published Year
|
2014 |
|
Journal
|
Antiviral therapy |
|
Title
|
Screening and identification of a novel adefovir dipivoxil resistance associated mutation, rtN236V, of HBV from a large cohort of HBV-infected patients. |
|
Author
|
Liu Y,Liu W,Li X,Xu Z,Wang X,Li C,Chen L,Xin S,Xu D |
|
Evidence
|
RESULTS: rtN236V was detected in six ADV-refractory patients; signature ADV-resistant mutations rtA181V and rtN236T were detected in 1,311 patients.
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HBV Mutation Detail Information