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Mutation Information
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Mutation Site
|
L180I |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181T+rt.M204I+rt.L180I+rt.L180M+rt.V173L |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26309637
|
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Disease
|
Chronic hepatitis B
|
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Published Year
|
2015 |
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Journal
|
International journal of clinical and experimental medicine |
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Title
|
Detection and analysis of resistance mutations of hepatitis B virus. |
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Author
|
He X,Wang F,Huang B,Chen P,Zhong L |
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Evidence
|
Single base mutations included L180M, M204I, M204V, V207M, S213T, N/H238T, T184A, V214A, N236A, V173L, L180M/I, A181T, N236T and N/H238T/A. Of these mutations, M204I had the highest detection rate, followed by L180M, M204V and V173L (Figure 1).
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HBV Mutation Detail Information