HBV Mutation Detail Information

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Mutation Information
Mutation Site L229V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Country beijing;China
Literature Information
PubMed PMID 22398037
Disease Chronic hepatitis B
Published Year 2012
Journal Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Title The rtL229 substitutions in the reverse transcriptase region of hepatitis B virus (HBV) polymerase are potentially associated with lamivudine resistance as a compensatory mutation.
Author Ji D,Liu Y,Li L,Xu Z,Si LL,Dai JZ,Li X,Wang L,Yao Z,Xin SJ,Chen GF,Xu D
Evidence Individual substitution incidences were 2.77%, 0.97%, 0.83% and 0.55% for rtL229V, rtL229F, rtL229M and rtL229W, respectively.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation