|
Mutation Information
|
Mutation Site
|
A194T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204V+rt.L180M+rt.A194T |
|
Relevant Drug
|
tenofovir (TDF) |
|
Country
|
Australia |
Literature Information
|
PubMed PMID
|
19178592
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2009 |
|
Journal
|
HIV medicine |
|
Title
|
Prolonged use of tenofovir in HIV/hepatitis B virus (HBV)-coinfected individuals does not lead to HBV polymerase mutations and is associated with persistence of lamivudine HBV polymerase mutations. |
|
Author
|
Audsley J,Arrifin N,Yuen LK,Ayres A,Crowe SM,Bartholomeusz A,Locarnini SA,Mijch A,Lewin SR,Sasadeusz J |
|
Evidence
|
The previously identified putative TDF-resistance mutations, rtA194T+rtL180M+rtM204V, were not detected in any individual.
|
|
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HBV Mutation Detail Information