HBV Mutation Detail Information

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Mutation Information
Mutation Site L180I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.M204I+rt.L180I
Genotype/Subtype A;F
Relevant Drug lamivudine (LAM)
Country Brazil
Literature Information
PubMed PMID 18211717
Disease Chronic hepatitis B
Published Year 2008
Journal BMC microbiology
Title Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil.
Author Bottecchia M,Souto FJ,O KM,Amendola M,Brandão CE,Niel C,Gomes SA
Evidence At last, three patients displayed a single (rtM204I, patient 05-hac) or double (rtL180I/rtM204I, 11-hgg and 01-ufmt) mutation leading to the YIDD motif.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation