Mutation Information
Mutation Site
|
L180I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.M204I+rt.L180I |
Genotype/Subtype
|
A;F |
Relevant Drug
|
lamivudine (LAM) |
Country
|
Brazil |
Literature Information
PubMed PMID
|
18211717
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2008 |
Journal
|
BMC microbiology |
Title
|
Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil. |
Author
|
Bottecchia M,Souto FJ,O KM,Amendola M,Brandão CE,Niel C,Gomes SA |
Evidence
|
At last, three patients displayed a single (rtM204I, patient 05-hac) or double (rtL180I/rtM204I, 11-hgg and 01-ufmt) mutation leading to the YIDD motif.
|
|
|