|
Mutation Information
|
Mutation Site
|
I269T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV);telbivudine (LDT) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
19302908
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Clinical therapeutics |
|
Title
|
Evolution of hepatitis B virus polymerase mutations in a patient with HBeAg-positive chronic hepatitis B virus treated with sequential monotherapy and add-on nucleoside/nucleotide analogues. |
|
Author
|
Wang F,Wang H,Shen H,Meng C,Weng X,Zhang W |
|
Evidence
|
At week 108, after the patient had been receiving ADV + LDT combination therapy for 22 weeks, rtS202G and rtI269T had emerged, representing 28.
|
|
|
HBV Mutation Detail Information