|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
17086064
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2006 |
|
Journal
|
AIDS (London, England) |
|
Title
|
A novel hepatitis B virus mutation with resistance to adefovir but not to tenofovir in an HIV-hepatitis B virus-co-infected patient. |
|
Author
|
Lacombe K,Ollivet A,Gozlan J,Durantel S,Tran N,Girard PM,Zoulim F |
|
Evidence
|
A molecular virology analysis performed in an HIV-hepatitis B virus (HBV) co-infected patient showed the emergence of an unusual HBV polymerase gene mutation (rt A181T) under adefovir therapy
|
|
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HBV Mutation Detail Information