|
Mutation Information
|
Mutation Site
|
S550C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
11596084
|
|
Disease
|
HBV infection
|
|
Published Year
|
2001 |
|
Journal
|
Journal of medical virology |
|
Title
|
Residual hepatitis B virus particles in liver transplant recipients receiving lamivudine: PCR quantitation of HBV DNA and ELISA of preS1 antigen. |
|
Author
|
Petit MA,Buffello-Le Guillou D,Roche B,Dussaix E,Duclos-Vallée JC,Féray C,Samuel D |
|
Evidence
|
Among the three patients who did not respond to lamivudine, one had pol mutations (L450P and S550C) that had not been described previously, in addition to the common mutations within the YMDD locus and B domain.
|
|
|
HBV Mutation Detail Information