HBV Mutation Detail Information

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Mutation Information

Mutation Site	M552V
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Combined Mutation	p.M552V+p.L528M
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	10377169
Published Year	1999
Journal	The Journal of clinical investigation
Title	Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors.
Author	Ono-Nita SK,Kato N,Shiratori Y,Lan KH,Yoshida H,Carrilho FJ,Omata M
Evidence	In this study, susceptibility of wild-type and lamivudine-resistant HBV M552I, M552V, and L528M/M552V mutants to other reverse transcriptase inhibitors was investigated by transient transfection of full-length HBV DNA intoHuman hepatoma cells.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation