Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
clevudine (CLV);entecavir (ETV) |
Country
|
Korea |
Literature Information
PubMed PMID
|
21484144
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2011 |
Journal
|
Hepatology international |
Title
|
A comparison of 48-week treatment efficacy between clevudine and entecavir in treatment-naïve patients with chronic hepatitis B. |
Author
|
Shin SR,Yoo BC,Choi MS,Lee DH,Song SM,Lee JH,Koh KC,Paik SW |
Evidence
|
Two (3.4%) patients in clevudine group showed virologic breakthrough with rtM204I mutation using direct sequencing analysis.
|
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|