HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	s.W172S+s.W172*+rt.A181T
Relevant Drug	adefovir (ADV);tenofovir (TDF)
Country	Korea

Literature Information

PubMed PMID	24696492
Disease	Chronic hepatitis B
Published Year	2014
Journal	Journal of virology
Title	The impact of the hepatitis B virus polymerase rtA181T mutation on replication and drug resistance is potentially affected by overlapping changes in surface gene.
Author	Ahn SH,Park YK,Park ES,Kim JH,Kim DH,Lim KH,Jang MS,Choe WH,Ko SY,Sung IK,Kwon SY,Kim KH
Evidence	The impact of the hepatitis B virus polymerase rtA181T mutation on replication and drug resistance is potentially affected by overlapping changes in surface gene.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation