|
Mutation Information
|
Mutation Site
|
L217R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
A |
|
Relevant Drug
|
adefovir (ADV);lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
15577546
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2004 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment. |
|
Author
|
Schildgen O,Schewe CK,Vogel M,Däumer M,Kaiser R,Weitner L,Matz B,Rockstroh JK |
|
Evidence
|
In two isolates we identified hepatitis B virus DNA polymerase mutation L217R, in one case we found multiple frameshifts in the same region.
|
|
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HBV Mutation Detail Information