|
Mutation Information
|
Mutation Site
|
A181V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
India |
Literature Information
|
PubMed PMID
|
22720023
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Hepatitis B virus gene mutations in liver diseases: a report from New Delhi. |
|
Author
|
Malik A,Singhal DK,Albanyan A,Husain SA,Kar P |
|
Evidence
|
17.9% patients with cirrhosis and 24.6% hepatocellular carcinoma cases were ADV-resistant with rtA181T/V mutations in the S-gene.
|
|
|
HBV Mutation Detail Information