|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
s.W172*+rt.A181T |
|
Genotype/Subtype
|
D |
Literature Information
|
PubMed PMID
|
27871021
|
|
Published Year
|
2017 |
|
Journal
|
Virology |
|
Title
|
Stop codons in the hepatitis B surface proteins are enriched during antiviral therapy and are associated with host cell apoptosis. |
|
Author
|
Colledge D,Soppe S,Yuen L,Selleck L,Walsh R,Locarnini S,Warner N |
|
Evidence
|
Cell line were transfected with infectious HBV clones encoding surface stop codons rtM204I/sW196*, rtA181T/sW172*, rtV191I/sW182*, and a panel of substitutions in the surface proteins.
|
|
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HBV Mutation Detail Information