All Curated Mutation Sites in HBV

The VM annotation module provides researchers who are interested in VMs with annotations of reported pathogenic mutations in HBV related to human diseases easily. The curated mutation information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region or Disease

*Please select one option you are interested in, the page will be automatically redirected.

Virus Gene/Protein/Region:

Disease:

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	19272629	K130M	X	D G R CI C	View
2	19272629	V131I	X	D G R CI C	View
3	15543574	I127N	X	G S CI C	View
4	15543574	I127T	X	G S CI C	View
5	15543574	K130M	X	G S CI C	View
6	15543574	V131I	X	G S CI C	View
7	19272629	R95K	X	G R CI C	View
8	19272629	W123L	X	G R CI C	View
9	19272629	S88C	X	G R CI C	View
10	19272629	K118R	X	G R CI C	View
11	24637457	S11P	X	G R S C	View
12	24637457	A31S	X	G R S C	View
13	24637457	R32G	X	G R S C	View
14	24637457	S33P	X	G R S C	View
15	24637457	V37L	X	G R S C	View
16	24637457	Q87H	X	G R S C	View
17	24637457	L98C	X	G R S C	View
18	24637457	E126R	X	G R S C	View
19	24637457	V133Y	X	G R S C	View
20	24637457	A144H	X	G R S C	View
21	24637457	P145Q	X	G R S C	View
22	24637457	L30F	X	G R S C	View
23	24637457	M103D	X	G R S C	View
24	26890489	G1613A	X	G S CI C	View
25	28753615	G1613A	X	G R S C	View
26	29285238	F132I	X	G R S C	View
27	29285238	F132R	X	G R S C	View
28	29285238	F132Y	X	G R S C	View
29	29285238	H94Y	X	G R S C	View
30	29285238	I127T	X	G R S C	View
31	29285238	K130M	X	G R S C	View
32	29285238	V131I	X	G R S C	View
33	29285238	V131L	X	G R S C	View
34	29285238	S42P	X	G R S C	View
35	29285238	A47T	X	G R S C	View
36	11596083	S31L	X	G S C	View
37	11596083	C143F	X	G S C	View
38	12727536	K130M	X	D G C	View
39	12727536	K95Q	X	D G C	View
40	12727536	N118T	X	D G C	View
41	12727536	V131I	X	D G C	View
42	17652471	C1485T	X	G S C	View
43	17652471	G1499H	X	G S C	View
44	17652471	G1613A	X	G S C	View
45	17652471	T1479C	X	G S C	View
46	17652471	P38S	X	G S C	View
47	17652471	T36P	X	G S C	View
48	17888035	C1485T	X	G R C	View
49	17888035	C1653T	X	G R C	View
50	17888035	A1762T	X	G R C	View
51	17888035	G1764A	X	G R C	View
52	18649329	K130M	X	G S C	View
53	18649329	V131I	X	G S C	View
54	18649329	I127T	X	G S C	View
55	19431214	A44L	X	G R C	View
56	19431214	P38S	X	G R C	View
57	19574418	G1613A	X	G S C	View
58	19574418	C1485T	X	G S C	View
59	19574418	A1499G	X	G S C	View
60	19574418	G1499H	X	G S C	View
61	19574418	T1479C	X	G S C	View
62	20513074	D48N	X	R S C	View
63	22014121	G1727A	X	G S C	View
64	22617152	V21A	X	G R C	View
65	22617152	Q87R	X	G R C	View
66	24632784	V30L	X	G S C	View
67	24637457	G50R	X	R S C	View
68	24637457	T36A	X	R S C	View
69	25281206	C1673T	X	G S C	View
70	25283864	A1632C	X	G R C	View
71	25283864	A1635C	X	G R C	View
72	25283864	A1726C	X	G R C	View
73	25283864	A1727T	X	G R C	View
74	25283864	C1653T	X	G R C	View
75	25283864	C1730G	X	G R C	View
76	26706415	A10R	X	G S C	View
77	26706415	K130M	X	G S C	View
78	26706415	S144R	X	G S C	View
79	26706415	V131I	X	G S C	View
80	26715821	V5M	X	G R C	View
81	28591184	P42T	X	G S C	View
82	30472417	F30V	X	G R C	View
83	30570771	S29P	X	G S C	View
84	32532295	G1613A	X	G S C	View
85	32532295	C1653T	X	G S C	View
86	32532295	G1386AC	X	G S C	View
87	32532295	G1515A	X	G S C	View
88	32532295	A1516C	X	G S C	View
89	32532295	T1633A	X	G S C	View
90	32532295	T1485C	X	G S C	View
91	32532295	V5ML	X	G S C	View
92	32532295	D48AN	X	G S C	View
93	32532295	H94Y	X	G S C	View
94	32532295	Q87L	X	G S C	View
95	32532295	S38P	X	G S C	View
96	33603102	A12S	X	G S C	View
97	33603102	P33S	X	G S C	View
98	33603102	P46S	X	G S C	View
99	33603102	T36D	X	G S C	View
100	33603102	T36G	X	G S C	View
101	33603102	T36A	X	G S C	View
102	33947693	A1726C	X	R CI C	View
103	33947693	C1828A	X	R CI C	View
104	33947693	G1229A	X	R CI C	View
105	33947693	C1230G	X	R CI C	View
106	33947693	A1383C	X	R CI C	View
107	10534721	S33P	X	G C	View
108	10534721	K82D	X	G C	View
109	10534721	Q84H	X	G C	View
110	10534721	P85Q	X	G C	View
111	10534721	V129L	X	G C	View
112	10745228	S41P	X	G C	View
113	16080797	A1721G	X	G R	View
114	16080797	T12A	X	G R	View
115	16080797	Q8K	X	G R	View
116	16080797	S33P	X	G R	View
117	16080797	D110E	X	G R	View
118	16080797	D48N	X	G R	View
119	16080797	K130M	X	G R	View
120	16080797	M130K	X	G R	View
121	16080797	P40S	X	G R	View
122	16080797	R103W	X	G R	View
123	16080797	R87W	X	G R	View
124	16080797	T106P	X	G R	View
125	16080797	V131I	X	G R	View
126	17464459	C1653T	X	CI C	View
127	17825452	R87G	X	G R	View
128	17825452	R87W	X	G R	View
129	17825452	R87R	X	G R	View
130	17825452	L123S	X	G R	View
131	17825452	L123L	X	G R	View
132	17825452	K130M	X	G R	View
133	17825452	K130K	X	G R	View
134	17888035	P38S	X	G C	View
135	17888035	H94Y	X	G C	View
136	17888035	K130M	X	G C	View
137	17888035	V131I	X	G C	View
138	18216102	A1762T	X	G C	View
139	18216102	G1764A	X	G C	View
140	18216102	K130M	X	G C	View
141	18216102	V131I	X	G C	View
142	18551606	H94Y	X	G C	View
143	18551606	I127N	X	G C	View
144	18551606	I127T	X	G C	View
145	18551606	K130M	X	G C	View
146	18551606	P38S	X	G C	View
147	18551606	V131I	X	G C	View
148	18551606	V5L	X	G C	View
149	18551606	V5M	X	G C	View
150	18551606	A1762T	X	G C	View
151	18551606	G1764A	X	G C	View
152	18952249	V5M	X	R C	View
153	19099581	K130M	X	G C	View
154	19099581	V131I	X	G C	View
155	19431214	A36T	X	R C	View
156	20196797	D107V	X	S C	View
157	20196797	I127T	X	S C	View
158	20699378	C1653T	X	R C	View
159	20699378	G1613A	X	R C	View
160	20699378	T1753C	X	R C	View
161	21063480	C1653T	X	G C	View
162	21063480	G1613A	X	G C	View
163	21063480	K130M	X	G C	View
164	21063480	V131I	X	G C	View
165	21063480	A36T	X	G C	View
166	21063480	P38S	X	G C	View
167	21063480	A44L	X	G C	View
168	21063480	H94Y	X	G C	View
169	22095534	C1638T	X	G C	View
170	22095534	T1631C	X	G C	View
171	22095534	C1495T	X	G C	View
172	22095534	C1505A	X	G C	View
173	23104706	C1653T	X	G C	View
174	23383661	T1753V	X	G C	View
175	23852705	C1653T	X	S C	View
176	23852705	H94Y	X	S C	View
177	24006435	G1719T	X	G C	View
178	24006435	T1673C	X	G C	View
179	24006435	T1674C	X	G C	View
180	24006435	T1674G	X	G C	View
181	24973814	C1653T	X	S C	View
182	25283864	A1762T	X	R C	View
183	25283864	G1764A	X	R C	View
184	25283864	T1753C	X	R C	View
185	25333524	H94Y	X	S C	View
186	25333524	I127T	X	S C	View
187	25333524	K130M	X	S C	View
188	25333524	V131I	X	S C	View
189	25333524	C1653T	X	S C	View
190	26478663	C1638T	X	G C	View
191	26571502	I127T	X	S C	View
192	26571502	H94Y	X	S C	View
193	26571502	K130M	X	S C	View
194	26571502	V131I	X	S C	View
195	26571502	M130K	X	S C	View
196	26571502	T127I	X	S C	View
197	26571502	I131V	X	S C	View
198	26647737	G1719T	X	G C	View
199	27340355	C1653T	X	G C	View
200	27340355	T1753V	X	G C	View
201	27727182	A1762T	X	R C	View
202	27727182	C1653T	X	R C	View
203	27727182	G1613A	X	R C	View
204	27727182	G1764A	X	R C	View
205	27727182	T1753V	X	R C	View
206	27727182	C1766T	X	R C	View
207	27727182	T1768A	X	R C	View
208	27727182	H94Y	X	R C	View
209	27727182	I127T	X	R C	View
210	27727182	I127N	X	R C	View
211	27727182	I127S	X	R C	View
212	27727182	K130M	X	R C	View
213	27727182	V131I	X	R C	View
214	27727182	F132Y	X	R C	View
215	27824315	A1499G	X	S C	View
216	27824315	G1764A	X	S C	View
217	27824315	A1726T	X	S C	View
218	27824315	A1762T	X	S C	View
219	29393485	I127T	X	G R	View
220	29393485	T36P	X	G R	View
221	29393485	V5M	X	G R	View
222	29393485	A1479C	X	G R	View
223	29393485	G1386A	X	G R	View
224	30472417	K130M	X	R C	View
225	30472417	V131I	X	R C	View
226	30570771	K130M	X	S C	View
227	31434918	C1653T	X	G C	View
228	31565220	I127L	X	R C	View
229	31565220	I127N	X	R C	View
230	31565220	I127S	X	R C	View
231	31565220	I127T	X	R C	View
232	31565220	K130M	X	R C	View
233	31565220	R87G	X	R C	View
234	31565220	R87W	X	R C	View
235	31565220	V131I	X	R C	View
236	31565220	T36P	X	R C	View
237	31565220	L37I	X	R C	View
238	31565220	P38S	X	R C	View
239	31565220	S43P	X	R C	View
240	31565220	A44V	X	R C	View
241	31565220	A44T	X	R C	View
242	31565220	P46S	X	R C	View
243	31565220	H86P	X	R C	View
244	31565220	H86R	X	R C	View
245	31565220	H94Y	X	R C	View
246	31565220	L98I	X	R C	View
247	31565220	T105A	X	R C	View
248	31565220	L123S	X	R C	View
249	31565220	L123V	X	R C	View
250	31601912	A44V	X	R C	View
251	31601912	F73V	X	R C	View
252	31601912	S146A	X	R C	View
253	31601912	S147P	X	R C	View
254	31601912	C1589A	X	R C	View
255	31601912	T1590G	X	R C	View
256	31601912	C1504T	X	R C	View
257	31601912	T1809G	X	R C	View
258	31601912	T1812C	X	R C	View
259	31601912	T1404C	X	R C	View
260	31601912	A1437G	X	R C	View
261	31601912	C1450G	X	R C	View
262	31601912	G1464T	X	R C	View
263	31601912	A1467G	X	R C	View
264	31601912	G1479A	X	R C	View
265	31601912	G1482C	X	R C	View
266	31601912	T1512G	X	R C	View
267	31601912	C1594T	X	R C	View
268	31601912	G1630A	X	R C	View
269	31601912	G1635A	X	R C	View
270	31601912	R72R	X	R C	View
271	31601912	S11P	X	R C	View
272	31601912	S22G	X	R C	View
273	31601912	P26R	X	R C	View
274	31601912	A31S	X	R C	View
275	31601912	R32G	X	R C	View
276	31601912	A36T	X	R C	View
277	31601912	V37L	X	R C	View
278	31601912	S47A	X	R C	View
279	31601912	T74I	X	R C	View
280	31601912	R86H	X	R C	View
281	31601912	V88I	X	R C	View
282	31601912	M130K	X	R C	View
283	31601912	I131V	X	R C	View
284	8834018	T142T	X	R C	View
285	8834018	A143T	X	R C	View
286	33803998	V5M	X	G S	View
287	33803998	L5M	X	G S	View
288	33803998	T36P	X	G S	View
289	33803998	T36S	X	G S	View
290	33803998	T36A	X	G S	View
291	33803998	S101P	X	G S	View
292	33803998	S101A	X	G S	View
293	33803998	V131I	X	G S	View
294	15256984	G1390A	X	D	View
295	15256984	G1437A	X	D	View
296	15256984	A1574T	X	D	View
297	15256984	A1676T	X	D	View
298	15256984	A1703C	X	D	View
299	15256984	T1741C	X	D	View
300	15256984	C1449T	X	D	View
301	15256984	C1449A	X	D	View
302	15256984	A1511G	X	D	View
303	15256984	A1511T	X	D	View
304	15256984	G1634A	X	D	View
305	15256984	G1634T	X	D	View
306	15256984	C1637G	X	D	View
307	15256984	C1637T	X	D	View
308	16080797	S31P	X	R	View
309	16080797	V37I	X	R	View
310	16094714	F132Y	X	G	View
311	16094714	I127T	X	G	View
312	16094714	K130M	X	G	View
313	16094714	V131I	X	G	View
314	16094714	T1768A	X	G	View
315	16094714	T1753C	X	G	View
316	16094714	A1762T	X	G	View
317	16094714	G1764A	X	G	View
318	18266648	C1485T	X	C	View
319	18952249	H94Y	X	C	View
320	18952249	P38S	X	C	View
321	18952249	V5L	X	C	View
322	20160279	C1653T	X	C	View
323	20184927	I127M	X	C	View
324	21438026	K130M	X	G	View
325	21438026	V131I	X	G	View
326	21461076	C1485T	X	C	View
327	21461076	C1653T	X	C	View
328	21461076	G1386M	X	C	View
329	22178505	L30F	X	C	View
330	22178505	S144A	X	C	View
331	22178505	V88I	X	C	View
332	22178505	S31P	X	C	View
333	22178505	S43P	X	C	View
334	22178505	Q87R	X	C	View
335	22178505	H94R	X	C	View
336	24119014	G1764A	X	C	View
337	24119014	C1773T	X	C	View
338	24119014	C1715G	X	C	View
339	24119014	A1762T	X	C	View
340	24119014	K130M	X	C	View
341	24119014	V131I	X	C	View
342	24119014	V132V	X	C	View
343	24119014	T113E	X	C	View
344	24700252	V131I	X	C	View
345	24700252	K130M	X	C	View
346	25625002	C1766T	X	G	View
347	25625002	T1768A	X	G	View
348	25658544	G1613A	X	C	View
349	25658544	C1653T	X	C	View
350	25658544	C1479A	X	C	View
351	25658544	C1479T	X	C	View
352	25658544	A1727G	X	C	View
353	25658544	A1703G	X	C	View
354	25658544	A1752G	X	C	View
355	25942596	A1383C	X	G	View
356	25942596	C1485T	X	G	View
357	25942596	C1631T	X	G	View
358	25942596	C1653T	X	G	View
359	25942596	G1719T	X	G	View
360	25942596	T1800C	X	G	View
361	25942596	R1479C	X	G	View
362	25942596	R1479T	X	G	View
363	25942596	R1479Y	X	G	View
364	28325923	S54P	X	C	View
365	28325923	L55F	X	C	View
366	28325923	R56P	X	C	View
367	28325923	L58P	X	C	View
368	28325923	C69P	X	C	View
369	28654219	A1762T	X	G	View
370	28654219	G1764A	X	G	View
371	28654219	K130M	X	G	View
372	28654219	V131I	X	G	View
373	29479565	A1479T	X	C	View
374	30229977	K130M	X	C	View
375	30229977	V131I	X	C	View
376	30229977	V131L	X	C	View
377	30706588	T1719G	X	G	View
378	31086664	C1505A	X	C	View
379	31086664	T1631C	X	C	View
380	31086664	C1638T	X	C	View
381	31086664	C1726A	X	C	View
382	31341154	A12S	X	C	View
383	31341154	A12T	X	C	View
384	31341154	K130M	X	C	View
385	31341154	L16F	X	C	View
386	31341154	L16P	X	C	View
387	31341154	N88V	X	C	View
388	31341154	V131I	X	C	View
389	31341154	K130*	X	C	View
390	31341154	S43V	X	C	View
391	31846615	I127T	X	C	View
392	31846615	K130M	X	C	View
393	31846615	V131I	X	C	View
394	31846615	F132Y	X	C	View
395	32283837	V5L	X	G	View
396	32283837	V5M	X	G	View
397	11002246	K130M	X		View
398	11002246	V131I	X		View
399	11287420	L100A	X		View
400	11287420	L98A	X		View
401	11287420	G99A	X		View
402	16080797	C1718T	X		View
403	16080797	G1714A	X		View
404	17622616	P101S	X		View
405	17622616	K130M	X		View
406	17622616	M130K	X		View
407	19439550	F132Y	X		View
408	19439550	K130M	X		View
409	19439550	V131I	X		View
410	21704589	V131I	X		View
411	21704589	K130M	X		View
412	21998953	A1762T	X		View
413	21998953	G1764A	X		View
414	23403838	T1699C	X		View
415	24346287	K130M	X		View
416	24346287	V131I	X		View
417	24346287	A1630G	X		View
418	24346287	G1721A	X		View
419	24346287	G1764A	X		View
420	24346287	A1762T	X		View
421	24346287	H86Y	X		View
422	24346287	E109D	X		View
423	24346287	A66T	X		View
424	24346287	A12T	X		View
425	25019072	K130M	X		View
426	25019072	V131I	X		View
427	30358169	S31A	X		View
428	30358169	S31D	X		View
429	31706164	N118K	X		View
430	31706164	E119D	X		View
431	33652602	S41A	X		View
432	33652602	T81D	X		View
433	33652602	T81A	X		View
434	33652602	S41D	X		View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
Drugs mentioned in the relevant literature.

G
Genotypes/subtypes mentioned in the relevant literature.

R
Reference genomes mentioned in the relevant literature.

S
Viral sequences mentioned in the relevant literature.

C
Geographical distribution of the source mentioned in the relevant literature.

CI
Clinical information is available in the relevant literature.

I
This mutation is related to the immune escape.


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