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Mutation Information
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Mutation Site
|
A12S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
X |
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Genotype/Subtype
|
D |
|
Country
|
Spain |
Literature Information
|
PubMed PMID
|
33603102
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2021 |
|
Journal
|
Scientific reports |
|
Title
|
Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients. |
|
Author
|
Cortese MF,González C,Gregori J,Casillas R,Carioti L,Guerrero-Murillo M,Riveiro-Barciela M,Godoy C,Sopena S,Yll M,Quer J,Rando A,Lopez-Martinez R,Pacín Ruiz B,García-García S,Esteban-Mur R,Tabernero D,Buti M,Rodríguez-Frías F |
|
Evidence
|
A genotype D-specific pattern of mutations (A12S/P33S/P46S/T36D-G) was identified in CI (median frequency, 81.7%), which determined a reduction in HBV DNA release of up to 1.5 log in vitro.
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HBV Mutation Detail Information