|
Mutation Information
|
Mutation Site
|
K130M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
X |
|
Amino acid_Mutation
|
A1762T |
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
30570771
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
|
Journal
|
Journal of medical virology |
|
Title
|
Hepatitis B virus in Mar del Plata, Argentina: Genomic characterization and evolutionary analysis of subgenotype F1b. |
|
Author
|
Torres MC,Civetta E,D'amico C,Barbini L |
|
Evidence
|
Within the ORF‐X, almost all the studied samples (39 of 46, 85%) showed mutations along their sequences. Only 12 (26%) presented the nt substitutions A1762T and G1764A at the BCP, associated to a decrease in HBeAg expression and translated to the K130M and V131I amino acid mutations at the X protein.
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|
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HBV Mutation Detail Information