|
Mutation Information
|
Mutation Site
|
V131I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
X |
|
Combined Mutation
|
x.V131I+x.K130M;x.V131I+x.K130M+x.N88V |
|
Country
|
Indonesia |
Literature Information
|
PubMed PMID
|
31341154
|
|
Disease
|
Hepatocellular carcinoma;
Chronic hepatitis B;
Liver cirrhosis
|
|
Published Year
|
2019 |
|
Journal
|
The Kobe journal of medical sciences |
|
Title
|
Association Between HBx Variations and Development of Severe Liver Disease Among Indonesian Patients. |
|
Author
|
Putri WA,Yano Y,Yamani LN,Lusida MI,Soetjipto,Liang Y,Mardian Y,Wasityastuti W,Hayashi Y |
|
Evidence
|
In addition, the double mutation K130M/V131I and the triple mutation N88V/K130M/V131I were associated with a 2.5 times higher risk of advanced liver disease.
|
|
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HBV Mutation Detail Information