Mutation Information
Mutation Site
|
I127T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
X |
Amino acid_Mutation
|
T1753C |
Country
|
England |
Literature Information
PubMed PMID
|
20196797
|
Disease
|
HBV infection
|
Published Year
|
2011 |
Journal
|
Journal of viral hepatitis |
Title
|
Diversity of hepatitis B virus infecting Malaysian candidate blood donors is driven by viral and host factors. |
Author
|
Meldal BH,Bon AH,Prati D,Ayob Y,Allain JP |
Evidence
|
Mutations in the BCP region were more commonly found in genotype C: T1753C [xI127T] (11/29 in genotype C vs 1/51 in genotype B, FE Test P < 0.0001), G1764A [xV131I] (14/29 in genotype C vs 4/51 in genotype B, FE Test P < 0.0001) and A1762T [xK130M]/G1764A (11/29 in genotype C vs 4/51 in genotype B, FE Test P = 0.0020).
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