Mutation Information
Mutation Site
|
A12T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
X |
Literature Information
PubMed PMID
|
24346287
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2014 |
Journal
|
British journal of cancer |
Title
|
HBx mutants differentially affect the activation of hypoxia-inducible factor-1α in hepatocellular carcinoma. |
Author
|
Liu LP,Hu BG,Ye C,Ho RL,Chen GG,Lai PB |
Evidence
|
To this end, six artificial HBx mutants have been established, including HA-A12T-HBx, HA-V44I-HBx, HA-A66T-HBx, HA-H86Y-HBx, HA-E109D-HBx and HA-K130M/V131I-HBx (Figure 1A).
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