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Mutation Information
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Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
X |
|
Combined Mutation
|
x.G1764A+x.A1762T |
|
Nucleotide_Mutation
|
K130M |
|
Viral Reference
|
GI289976881;
GI289976889 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
27727182
|
|
Disease
|
Hepatocellular carcinoma
|
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Published Year
|
2016 |
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Journal
|
International journal of molecular sciences |
|
Title
|
Potential Susceptibility Mutations in C Gene for Hepatitis B-Related Hepatocellular Carcinoma Identified by a Two-Stage Study in Qidong, China. |
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Author
|
Qu L,Zhang H,Liu J,Liu T,Shen X,Chen T,Ni Z,Lu C |
|
Evidence
|
A total of 10 mutations (including pre-S2 start codon mutation and pre-S deletion in pre-S gene, G1613A, C1653T, A1762T, and G1764A mutations in X gene, A2159G, A2189Y, G2203W, and C2288R mutations in C gene) showed an increased risk of HCC.
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HBV Mutation Detail Information