|
Mutation Information
|
Mutation Site
|
I127L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
X |
|
Viral Reference
|
D23678.1;
AB219430.1;
EF473977.1 |
|
Country
|
Surabaya; Indonesia |
Literature Information
|
PubMed PMID
|
31565220
|
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2019 |
|
Journal
|
Biomedical reports |
|
Title
|
Association between host TNF-α, TGF-β1, p53 polymorphisms, HBV X gene mutation, HBV viral load and the progression of HBV-associated chronic liver disease in Indonesian patients. |
|
Author
|
Wungu CDK,Amin M,Ruslan SEN,Purwono PB,Kholili U,Maimunah U,Setiawan PB,Lusida MI,Soetjipto S,Handajani R |
|
Evidence
|
Significant differences in viral load were found in HBV-infected patients who had X gene mutations, such as R87W/G, I127L/T/N/S and K130M/V131I mutations (P<0.05).
|
|
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HBV Mutation Detail Information