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Mutation Information
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Mutation Site
|
L98A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
X |
|
Combined Mutation
|
x.L100A+x.L98A |
Literature Information
|
PubMed PMID
|
11287420
|
|
Published Year
|
2001 |
|
Journal
|
The Journal of biological chemistry |
|
Title
|
Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway. |
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Author
|
Forgues M,Marrogi AJ,Spillare EA,Wu CG,Yang Q,Yoshida M,Wang XW |
|
Evidence
|
Mutations at the two conserved leucine residues to alanine at the NES motif (L98A,L100A) resulted in a nuclear redistribution of HBx.
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HBV Mutation Detail Information