HBV Mutation Detail Information

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Mutation Information
Mutation Site M130K
Mutation Type Amino acid level
Gene/Protein/Region Type X
Literature Information
PubMed PMID 17622616
Published Year 2007
Journal The Journal of general virology
Title Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53.
Author Jung JK,Kwun HJ,Lee JO,Arora P,Jang KL
Evidence We found that only the hbx2 derivatives containing Ser-101 instead of Pro-101 (hbx2 P101S and hbx2 P101S/M130K) downregulated the β-catenin level, to the level obtained with HBX3 (Fig. 2a, bF2).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation