Mutation Information
Mutation Site
|
K130M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
X |
Literature Information
PubMed PMID
|
11002246
|
Disease
|
Chronic hepatitis B;
Hepatocellular carcinoma
|
Published Year
|
2000 |
Journal
|
Journal of medical virology |
Title
|
Hepatitis B virus X gene variability in French-born patients with chronic hepatitis and hepatocellular carcinoma. |
Author
|
Venard V,Corsaro D,Kajzer C,Bronowicki JP,Le Faou A |
Evidence
|
The changes K130M and V131I, considered as "hot spot mutations," were found in strains of HCC patients carrying an ayw subtype of the HBV genome but not in the ones of chronically infected patients.
|
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