|
Mutation Information
|
Mutation Site
|
I127T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
X |
|
Genotype/Subtype
|
C |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
18551606
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis;
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Journal of medical virology |
|
Title
|
Hepatitis B virus X mutations occurring naturally associated with clinical severity of liver disease among Korean patients with chronic genotype C infection. |
|
Author
|
Kim HJ,Park JH,Jee Y,Lee SA,Kim H,Song BC,Yang S,Lee M,Yoon JH,Kim YJ,Lee HS,Hwang ES,Kook YH,Kim BJ |
|
Evidence
|
All five mutation types (V5M/L, P38S, H94Y, I127T/N, and K130M and V131I) affecting the six codons were found to be related significantly to clinical severity.
|
|
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HBV Mutation Detail Information