|
Mutation Information
|
Mutation Site
|
A44L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
X |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
AB033550
|
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
19431214
|
|
Disease
|
Occult HBV infection;
Hepatocellular carcinoma
|
|
Published Year
|
2009 |
|
Journal
|
International journal of cancer |
|
Title
|
A study on sequence variations in pre-S/surface, X and enhancer II/core promoter/precore regions of occult hepatitis B virus in non-B, non-C hepatocellular carcinoma patients in Taiwan. |
|
Author
|
Chen CH,Changchien CS,Lee CM,Tung WC,Hung CH,Hu TH,Wang JH,Wang JC,Lu SN |
|
Evidence
|
Compared with the HBsAg-positive HCC controls, occult HBV-infected HCC patients had higher frequencies of M1I and Q2K in pre-S2 gene, G185R and S210N in surface gene, A36T and A44L in X gene, and G1721A in enhancer II gene, and had lower rates of pre-S deletions and A1762T/G1764A, A1846T, G1896A and G1899A in core promoter/precore genes.
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HBV Mutation Detail Information