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Mutation Information
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Mutation Site
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E119D |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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X |
Literature Information
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PubMed PMID
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31706164
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Published Year
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2020 |
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Journal
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Virology |
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Title
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Residues Asn118 and Glu119 of hepatitis B virus X protein are critical for HBx-mediated inhibition of RIG-I-MAVS signaling. |
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Author
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Wang F,Shen F,Wang Y,Li Z,Chen J,Yuan Z |
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Evidence
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Two amino acid substitutions of HBx were introduced to wild-type pHBV1.3 (gtB) and pHBV3.8 (gtC) plasmids to produce HBV variants, that is, HBV gtB mutant (N118K, E119D) and HBV gtC mutant (K118N, D119E).
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HBV Mutation Detail Information