HBV Mutation Detail Information

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Mutation Information

Mutation Site	A10R
Mutation Type	Amino acid level
Gene/Protein/Region Type	X
Genotype/Subtype	C
Country	China

Literature Information

PubMed PMID	26706415
Disease	Hepatocellular carcinoma
Published Year	2016
Journal	Cancer letters
Title	A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines.
Author	Shi Y,Wang J,Wang Y,Wang A,Guo H,Wei F,Mehta SR,Espitia S,Smith DM,Liu L,Zhang Y,Chen D
Evidence	These positions anchored the signature sequence which is able to classify variants with 75.5% accuracy, suggesting that A10R and S144R mutants are involved in HBV-related hepatocarcinogenesis.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation