Mutation Information
Mutation Site
|
K130M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
X |
Literature Information
PubMed PMID
|
17622616
|
Published Year
|
2007 |
Journal
|
The Journal of general virology |
Title
|
Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53. |
Author
|
Jung JK,Kwun HJ,Lee JO,Arora P,Jang KL |
Evidence
|
Among the six amino acid residues that are different between HBXX3 and hbx2 (Fig. 2a), the two substitutions, S101P and K130M, are known to be critical for the differential regulation of p21Waf1 expression (Kwun & Jang, 2004).
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