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Mutation Information
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Mutation Site
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P101S |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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X |
Literature Information
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PubMed PMID
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17622616
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Published Year
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2007 |
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Journal
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The Journal of general virology |
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Title
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Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53. |
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Author
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Jung JK,Kwun HJ,Lee JO,Arora P,Jang KL |
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Evidence
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We found that only the hbx2 derivatives containing Ser-101 instead of Pro-101 (hbx 2P101S and hbx 2P101S/M130K) downregulated the β-catenin level, to the level obtained with HBX3 (Fig. 2a, bF2).
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HBV Mutation Detail Information