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Overview of HBV Mutation, Integration-Cistrome Factor Overlap and Target gene
Hepatitis B virus (HBV)
is a partially double-stranded DNA virus, a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of viruses.
Size:
3020–3320 nucleotides long (for the full length strand) and 1700–2800 nucleotides long (for the short length strand)
[RefSeq: NC_003977.1]
Encoding:
S
,
X
,
C
,
P
,
BCP
Human Disease:
Infection with HBV can lead to
Chronic hepatitis B
,
Liver cirrhosis
,
Hepatocellular carcinoma
, etc.
Click here to see all HBV associated human diseases
Drug:
The long-term efficacy of drug can induce the emergence of drug resistant virus mutants, some common antiviral drug such as
lamivudine
,
entecavir
,
tenofovir
,
telbivudine
,
adefovir
,
rituximab
,
ganciclovir
can produce HBV mutants
rtM204I
,
rtL180M
/
rtM204V
,
sT118K
,
xK130M
, etc.
Click here to see more HBV RT drug resistance mutations.
Click the blue font on the page to view detailed information.
The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale".
HBV Mutation Info
Only show 100 info
Click here to see all HBV Mutation Sites
ID
PMID
Mutation
Gene/Protein/Region
Description
Detail