Overview of HBV Mutation, Integration-Cistrome Factor Overlap and Target gene


Hepatitis B virus (HBV) is a partially double-stranded DNA virus, a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of viruses.
Size: 3020–3320 nucleotides long (for the full length strand) and 1700–2800 nucleotides long (for the short length strand) [RefSeq: NC_003977.1]
Encoding: S, X, C, P, BCP
Human Disease: Infection with HBV can lead to Chronic hepatitis B, Liver cirrhosis, Hepatocellular carcinoma, etc. Click here to see all HBV associated human diseases
Drug: The long-term efficacy of drug can induce the emergence of drug resistant virus mutants, some common antiviral drug such as lamivudine, entecavir, tenofovir, telbivudine, adefovir, rituximab, ganciclovir can produce HBV mutants rtM204I, rtL180M/rtM204V, sT118K, xK130M, etc. Click here to see more HBV RT drug resistance mutations.

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The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale".



HBV Mutation Info
Only show 100 info Click here to see all HBV Mutation Sites
ID PMID Mutation Gene/Protein/Region Description Detail