Overview of AAV2 Mutation, Integration-Cistrome Factor Overlap and Target gene

Adenovirus Associated Virus Type 2 (AAV2) is a small virus that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in turn belongs to the family Parvoviridae. They are small (20 nm) replication-defective, nonenveloped viruses.Serotype 2 (AAV2) has been the most extensively examined so far. AAV2 presents natural tropism towards skeletal muscles, neurons, vascular smooth muscle cells and hepatocytes.
Size: ～4679 nucleotides long [RefSeq: AF043303.1]
Human Disease: Hepatocellular carcinoma.

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The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale."

AAV2 Overlap Info between Viral Integration Fragments and Cistrome Factors

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DVID	Chromosome	Histone Modification	Transcription Factor Binding Site	Chromatin Accessibility	Sum of Overlapped Records	Detail
2000007	chr4	1122	15		1137	View
2000008	chr4	519	9		528	View
2000009	chr4	240	66	3	309	View
2100001	chr4	78	1	3	82	View
2000014	chr4	44			44	View
2000015	chr4	44			44	View
2000016	chr4	44			44	View
2000017	chr4	42	1		43	View

AAV2 Target Gene Info

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ID	Target gene	Virus	Type	Literature Count	Detail
1	CCNE1	AAV2	Oncogene	3	View
2	INHBE	AAV2		1	View
3	TNFSF10	AAV2		1	View
4	KMT2B	AAV2		2	View
5	MACROH2A2	AAV2		1	View
6	TERT	AAV2		2	View
7	CCNA2	AAV2		3	View
8	NKAIN3	AAV2		1	View