Overview of HTLV1 Mutation, Integration-Cistrome Factor Overlap and Target gene

Human T-cell Lymphotropic Virus Type-1 (HTLV1), or human T-lymphotropic virus type 1, also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseases including very aggressive adult T-cell lymphoma (ATL), HTLV-I-associated myelopathy, uveitis, Strongyloides stercoralis hyper-infection and some other diseases.
Size: ～9034 nucleotides [RefSeq: AB513134]
Encoding: CA, Tax, Gp46, Rex, 5′LTR, 3′LTR and so on
Human Disease: Infection with HBV can lead to Adult T cell leukemia/lymphoma, etc. Click here to see all HTLV1 associated human diseases

Click the blue font on the page to view detailed information.
The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale."

HTLV1 Mutation Info

Only show 100 info Click here to see all HTLV1 Mutation Sites

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	22947305	A184G	5′LTR	R S CI C	View
2	22947305	G232A	5′LTR	R S CI C	View
3	25830656	L55P	Gp46	R S C	View
4	17067264	C7401T	Tax	R S C	View
5	17067264	C7920T	Tax	R S C	View
6	17067264	C7982T	Tax	R S C	View
7	17067264	G8231A	Tax	R S C	View
8	17067264	T7914C	Tax	R S C	View
9	23800288	R112C	HBZ	R S C	View
10	23800288	S9P	HBZ	R S C	View
11	23800288	T95I	HBZ	R S C	View
12	23800288	Y477H	Gp21	R S C	View
13	23800288	C101T	HBZ	R S C	View
14	23800288	C336T	HBZ	R S C	View
15	23800288	P34L	P12	R S C	View
16	26472535	G153A	5′LTR	R S C	View
17	26472535	T165C	5′LTR	R S C	View
18	26472535	C167T	5′LTR	R S C	View
19	26472535	G199A	5′LTR	R S C	View
20	26472535	A207G	5′LTR	R S C	View
21	26472535	C215T	5′LTR	R S C	View
22	26472535	C219G	5′LTR	R S C	View
23	26472535	C219T	5′LTR	R S C	View
24	26472535	C268T	5′LTR	R S C	View
25	26472535	A298G	5′LTR	R S C	View
26	26472535	T301A	5′LTR	R S C	View
27	26472535	T301C	5′LTR	R S C	View
28	26472535	T345C	5′LTR	R S C	View
29	26472535	151Delta11	5′LTR	R S C	View
30	28420387	A149T	P30	R S C	View
31	28420387	A3963T	Pol	R S C	View
32	28420387	A7247G	HBZ	R S C	View
33	28420387	A7247G	P30	R S C	View
34	28420387	C5593A	Env	R S C	View
35	28420387	C6903T	P12	R S C	View
36	28420387	C7962T	Tax	R S C	View
37	28420387	D140G	P30	R S C	View
38	28420387	F19L	Env	R S C	View
39	28420387	G7273A	P30	R S C	View
40	28420387	G8211A	Tax	R S C	View
41	28420387	H137Q	Env	R S C	View
42	28420387	S304N	Env	R S C	View
43	28420387	L27R	P30	R S C	View
44	28420387	P23S	P12	R S C	View
45	28420387	Q323H	Pol	R S C	View
46	28420387	A221V	HBZ	R S C	View
47	28420387	S13P	HBZ	R S C	View
48	28420387	T5237C	Env	R S C	View
49	28420387	T6908G	P30	R S C	View
50	33835501	C585T	HBZ	R S C	View
51	33835501	G434A	HBZ	R S C	View
52	33835501	C272T	HBZ	R S C	View
53	33835501	T138C	HBZ	R S C	View
54	33835501	T77C	HBZ	R S C	View
55	33835501	V15M	HBZ	R S C	View
56	33835501	P65L	HBZ	R S C	View
57	33835501	R119Q	HBZ	R S C	View
58	33835501	I164V	HBZ	R S C	View
59	33835501	K184R	HBZ	R S C	View
60	31154802	G29S	P12	S C	View
61	31154802	F61L	P12	S C	View
62	31154802	P34L	P12	S C	View
63	31154802	S63P	P12	S C	View
64	31154802	S91P	P12	S C	View
65	31154802	F78L	P12	S C	View
66	31154802	L55F	P12	S C	View
67	29716616	F14S	Gp46	S C	View
68	29716616	C26S	Gp46	S C	View
69	29716616	I150V	Gp46	S C	View
70	29716616	L163I	Gp46	S C	View
71	29716616	L200H	Gp46	S C	View
72	29716616	L210H	Gp46	S C	View
73	29716616	L213P	Gp46	S C	View
74	29716616	L219I	Gp46	S C	View
75	29716616	L70I	Gp46	S C	View
76	29716616	N24H	Gp46	S C	View
77	29716616	N93D	Gp46	S C	View
78	29716616	S103P	Gp46	S C	View
79	29716616	S192P	Gp46	S C	View
80	29716616	S194T	Gp46	S C	View
81	29716616	S72G	Gp46	S C	View
82	27553711	G29S	P12	S C	View
83	27553711	F61L	P12	S C	View
84	27553711	P34L	P12	S C	View
85	27553711	S63P	P12	S C	View
86	27553711	S91P	P12	S C	View
87	27553711	C39R	P12	S C	View
88	27553711	D26N	P12	S C	View
89	27553711	L40F	P12	S C	View
90	27553711	L66P	P12	S C	View
91	27553711	P45L	P12	S C	View
92	27553711	P91S	P12	S C	View
93	27553711	R83C	P12	S C	View
94	27553711	R88K	P12	S C	View
95	27553711	S23P	P12	S C	View
96	27553711	S69G	P12	S C	View
97	23510700	F14S	Gp46	S C	View
98	23510700	C289R	Gp46	S C	View
99	23510700	D197N	Gp46	S C	View
100	23510700	F141S	Gp46	S C	View

HTLV1 Overlap Info between Viral Integration Fragments and Cistrome Factors

Click to see statistics heatmap of VIS-Factor Overlap in the human genome of HTLV1

Click to see histogram of VIS-Factor Overlap by chromosome of HTLV1

Click to see the overlap count of three factors and HTLV1 intergration fragments on the human chromosomes

Only show 100 info Click here to see all HTLV1 Integration Sites

DVID	Chromosome	Histone Modification	Transcription Factor Binding Site	Chromatin Accessibility	Sum of Overlapped Records	Detail
6100002	chr1	3854	9474	2113	15441	View
6100062	chr1	2350	7942	2090	12382	View
6400005	chr1	4522	2460	1276	8258	View
6000031	chr1	3978	2549	1464	7991	View
6000047	chr1	4112	1394	1021	6527	View
6000054	chr1	3675	1747	732	6154	View
6000063	chr1	2791	1709	1282	5782	View
6000065	chr1	996	2628	2080	5704	View
6000066	chr1	4167	1076	439	5682	View
6000070	chr1	2539	1638	1377	5554	View
6000071	chr1	2602	1746	1205	5553	View
6000085	chr1	3060	1258	767	5085	View
6000086	chr1	2566	1546	945	5057	View
6000087	chr1	2445	1002	1583	5030	View
6000105	chr1	1309	1601	1675	4585	View
6000107	chr1	2439	1021	1090	4550	View
6100077	chr1	3251	717	348	4316	View
6000121	chr1	3278	664	294	4236	View
6000124	chr1	2165	1391	628	4184	View
6000154	chr1	2440	605	619	3664	View
6000159	chr1	3139	242	214	3595	View
6000162	chr1	2254	768	529	3551	View
6000167	chr1	2939	368	141	3448	View
6000171	chr1	3066	207	114	3387	View
6000177	chr1	2330	519	459	3308	View
6000179	chr1	885	1158	1255	3298	View
6000192	chr1	2047	939	174	3160	View
6000220	chr1	2711	122	70	2903	View
6000222	chr1	2374	193	317	2884	View
6000233	chr1	2247	293	191	2731	View
6000242	chr1	2551	81	29	2661	View
6000240	chr1	2469	115	75	2659	View
6000256	chr1	2010	316	246	2572	View
6000259	chr1	2423	93	9	2525	View
6000267	chr1	2107	295	74	2476	View
6000285	chr1	1819	302	226	2347	View
6000304	chr1	603	857	781	2241	View
6000308	chr1	2124	39	29	2192	View
6000315	chr1	2107	37	4	2148	View
6000322	chr1	1396	343	393	2132	View
6000323	chr1	1758	210	155	2123	View
6000325	chr1	56	1088	969	2113	View
6000329	chr1	1857	121	117	2095	View
6000332	chr1	1513	257	307	2077	View
6000341	chr1	408	872	755	2035	View
6000349	chr1	1778	96	138	2012	View
6000358	chr1	1784	198	9	1991	View
6100069	chr1	1225	444	273	1942	View
6000383	chr1	611	503	715	1829	View
6000384	chr1	96	1025	701	1822	View
6000396	chr1	1224	256	286	1766	View
6000401	chr1	368	674	703	1745	View
6000411	chr1	1027	366	313	1706	View
6000442	chr1	1257	135	200	1592	View
6000456	chr1	1117	256	185	1558	View
6000464	chr1	7	915	590	1512	View
6000486	chr1	1130	186	127	1443	View
6000487	chr1	592	460	383	1435	View
6000500	chr1	318	477	612	1407	View
6000505	chr1	516	679	201	1396	View
6000512	chr1	282	443	636	1361	View
6000515	chr1	30	794	531	1355	View
6000578	chr1	959	117	122	1198	View
6000614	chr1	772	321	35	1128	View
6000617	chr1	29	655	442	1126	View
6000619	chr1	138	433	541	1112	View
6000668	chr1	899	69	31	999	View
6000680	chr1	682	161	151	994	View
6000688	chr1	45	692	241	978	View
6000690	chr1	13	667	296	976	View
6100063	chr1	184	534	221	939	View
6000716	chr1	788	59	87	934	View
6100001	chr1	181	529	199	909	View
6000758	chr1	753	68	60	881	View
6000764	chr1	278	333	265	876	View
6000783	chr1	534	160	166	860	View
6000790	chr1	789	56	8	853	View
6000810	chr1	340	282	211	833	View
6000821	chr1	448	315	54	817	View
6000826	chr1	620	61	132	813	View
6000841	chr1	485	222	92	799	View
6000842	chr1	787	11		798	View
6000866	chr1	485	179	101	765	View
6000874	chr1	619	39	103	761	View
6000903	chr1	10	564	155	729	View
6000944	chr1	659	32	4	695	View
6000955	chr1	680	4		684	View
6000978	chr1	639	22		661	View
6000987	chr1	42	242	372	656	View
6000990	chr1	550	48	57	655	View
6000991	chr1	43	242	370	655	View
6001032	chr1	16	526	94	636	View
6001033	chr1	200	159	276	635	View
6001034	chr1	465	131	31	627	View
6001061	chr1	475	78	56	609	View
6001103	chr1	389	64	130	583	View
6001109	chr1	337	161	81	579	View
6001123	chr1	34	379	164	577	View
6001133	chr1	415	50	106	571	View
6001165	chr1	127	307	121	555	View

HTLV1 Target Gene Info

Click to see correlation between gene expression and proportions of infiltrating immune cells of HTLV1

Only show 100 info Click here to see all HTLV1 Target Gene

ID	Target gene	Virus	Gene Function	Literature Count	Detail
1	FBXO31	HTLV1	Suppressor gene	2	View
2	WNT7A	HTLV1	Suppressor gene	1	View
3	CTCFL	HTLV1	Suppressor gene	1	View
4	FBXO32	HTLV1	Suppressor gene	1	View
5	PRKN	HTLV1	Suppressor gene	3	View
6	CBFA2T3	HTLV1	Suppressor gene	1	View
7	PER2	HTLV1	Suppressor gene	1	View
8	RASSF3	HTLV1	Suppressor gene	1	View
9	TMPRSS11A	HTLV1	Suppressor gene	1	View
10	RASSF4	HTLV1	Suppressor gene	1	View
11	BLCAP	HTLV1	Suppressor gene	1	View
12	GRIN2A	HTLV1	Suppressor gene	4	View
13	RASSF5	HTLV1	Suppressor gene	1	View
14	CTDSPL	HTLV1	Suppressor gene	2	View
15	DAPK1	HTLV1	Suppressor gene	3	View
16	BLM	HTLV1	Suppressor gene	1	View
17	PACRG	HTLV1	Suppressor gene	2	View
18	PINX1	HTLV1	Suppressor gene	1	View
19	LAT2	HTLV1	Suppressor gene	1	View
20	RASSF8	HTLV1	Suppressor gene	1	View
21	LATS1	HTLV1	Suppressor gene	1	View
22	BLNK	HTLV1	Suppressor gene	1	View
23	CIC	HTLV1	Suppressor gene	1	View
24	ING5	HTLV1	Suppressor gene	1	View
25	LATS2	HTLV1	Suppressor gene	2	View
26	SRGAP3	HTLV1	Suppressor gene	1	View
27	ARHGEF12	HTLV1	Suppressor gene	1	View
28	EFNA5	HTLV1	Suppressor gene	3	View
29	HBP1	HTLV1	Suppressor gene	1	View
30	PCGF2	HTLV1	Suppressor gene	1	View
31	SH3GLB1	HTLV1	Suppressor gene	2	View
32	DSP	HTLV1	Suppressor gene	1	View
33	VPS53	HTLV1	Suppressor gene	2	View
34	PLXNC1	HTLV1	Suppressor gene	2	View
35	MCM9	HTLV1	Suppressor gene	1	View
36	CTNNA2	HTLV1	Suppressor gene	3	View
37	RB1	HTLV1	Suppressor gene	1	View
38	BMF	HTLV1	Suppressor gene	1	View
39	CBX5	HTLV1	Suppressor gene	2	View
40	DEUP1	HTLV1	Suppressor gene	1	View
41	AFAP1L2	HTLV1	Suppressor gene	1	View
42	CPNE7	HTLV1	Suppressor gene	1	View
43	MAP2K4	HTLV1	Suppressor gene	1	View
44	TFAP2A	HTLV1	Suppressor gene	1	View
45	CACNA2D3	HTLV1	Suppressor gene	4	View
46	CTNNA3	HTLV1	Suppressor gene	4	View
47	OPCML	HTLV1	Suppressor gene	3	View
48	CNTNAP2	HTLV1	Suppressor gene	4	View
49	MCPH1	HTLV1	Suppressor gene	1	View
50	NEDD4L	HTLV1	Suppressor gene	3	View
51	WWOX	HTLV1	Suppressor gene	3	View
52	USP12	HTLV1	Suppressor gene	1	View
53	CTNNBIP1	HTLV1	Suppressor gene	2	View
54	SRPX	HTLV1	Suppressor gene	1	View
55	RAB7A	HTLV1	Suppressor gene	1	View
56	CCAR1	HTLV1	Suppressor gene	1	View
57	PAIP2	HTLV1	Suppressor gene	1	View
58	RBBP8	HTLV1	Suppressor gene	1	View
59	TNFAIP3	HTLV1	Suppressor gene	1	View
60	INPP4B	HTLV1	Suppressor gene	4	View
61	SYNPO2	HTLV1	Suppressor gene	2	View
62	EPAS1	HTLV1	Suppressor gene	1	View
63	FBXW7	HTLV1	Suppressor gene	1	View
64	SMYD4	HTLV1	Suppressor gene	1	View
65	TMEFF2	HTLV1	Suppressor gene	1	View
66	EGLN3	HTLV1	Suppressor gene	1	View
67	EPB41	HTLV1	Suppressor gene	1	View
68	PTPN1	HTLV1	Suppressor gene	1	View
69	ACVR1C	HTLV1	Suppressor gene	1	View
70	TBL2	HTLV1	Suppressor gene	1	View
71	VSNL1	HTLV1	Suppressor gene	2	View
72	BMPR2	HTLV1	Suppressor gene	1	View
73	CADM1	HTLV1	Suppressor gene	1	View
74	EHD3	HTLV1	Suppressor gene	1	View
75	PTPN12	HTLV1	Suppressor gene	2	View
76	EPB41L3	HTLV1	Suppressor gene	1	View
77	STRADA	HTLV1	Suppressor gene	1	View
78	PKD1	HTLV1	Suppressor gene	1	View
79	CADM2	HTLV1	Suppressor gene	4	View
80	PTPN13	HTLV1	Suppressor gene	1	View
81	CADM4	HTLV1	Suppressor gene	1	View
82	DCC	HTLV1	Suppressor gene	4	View
83	LSAMP	HTLV1	Suppressor gene	3	View
84	EHF	HTLV1	Suppressor gene	1	View
85	MAP3K4	HTLV1	Suppressor gene	2	View
86	RBL1	HTLV1	Suppressor gene	1	View
87	RBL2	HTLV1	Suppressor gene	1	View
88	ZDHHC2	HTLV1	Suppressor gene	1	View
89	ATM	HTLV1	Suppressor gene	1	View
90	ATMIN	HTLV1	Suppressor gene	1	View
91	PTPN2	HTLV1	Suppressor gene	3	View
92	TBX5	HTLV1	Suppressor gene	1	View
93	DCDC2	HTLV1	Suppressor gene	1	View
94	PPP2R2C	HTLV1	Suppressor gene	1	View
95	ARID2	HTLV1	Suppressor gene	2	View
96	ZNF292	HTLV1	Suppressor gene	3	View
97	BNIP3L	HTLV1	Suppressor gene	1	View
98	ANAPC1	HTLV1	Suppressor gene	1	View
99	CDKN2A	HTLV1	Suppressor gene	2	View
100	EI24	HTLV1	Suppressor gene	1	View


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