Overview of EBV Mutation, Integration-Cistrome Factor Overlap and Target gene

Epstein-Barr Virus (EBV), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. The virus is about 122–180 nm in diameter and is composed of a double helix of deoxyribonucleic acid (DNA) which contains about 172,000 base pairs and 85 genes. The DNA is surrounded by a protein nucleocapsid, which is surrounded by a tegument made of protein, which in turn is surrounded by an envelope containing both lipids and surface projections of glycoproteins, which are essential to infection of the host cell.
Size: ～171823 nucleotides [RefSeq: NC_007605]
Encoding: epstein-barr virus genome mainly encodes 86 genes: BXLF2, BZLF1, BGLF4, BARF1, BALF5, RPMS1 and so on
Human Disease: Infection with EBV can lead to Nasopharyngeal carcinoma, B-cell lymphoma, etc. Click here to see all EBV associated human diseases

Click the blue font on the page to view detailed information.
The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale."

EBV Mutation Info

Click here to see all EBV Mutation Sites

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	28328987	30_bp del	LMP1	R S CI C	View
2	28328987	D150A	LMP1	R S CI C	View
3	28328987	D150G	LMP1	R S CI C	View
4	28328987	F144I	LMP1	R S CI C	View
5	28328987	I124T	LMP1	R S CI C	View
6	28328987	I124V	LMP1	R S CI C	View
7	28328987	I152L	LMP1	R S CI C	View
8	28328987	L151I	LMP1	R S CI C	View
9	26593963	T114C	LMP1	R S CI C	View
10	26593963	G12A	LMP1	R S CI C	View
11	26593963	C158T	LMP1	R S CI C	View
12	26593963	T172C	LMP1	R S CI C	View
13	26593963	A184T	LMP1	R S CI C	View
14	26593963	C199T	LMP1	R S CI C	View
15	26593963	C207T	LMP1	R S CI C	View
16	26593963	G227A	LMP1	R S CI C	View
17	26593963	G233A	LMP1	R S CI C	View
18	26593963	G234T	LMP1	R S CI C	View
19	26593963	A238G	LMP1	R S CI C	View
20	26593963	G240A	LMP1	R S CI C	View
21	26593963	T242C	LMP1	R S CI C	View
22	26593963	C272G	LMP1	R S CI C	View
23	26593963	G284T	LMP1	R S CI C	View
24	26593963	A286G	LMP1	R S CI C	View
25	26593963	A314G	LMP1	R S CI C	View
26	26593963	C315T	LMP1	R S CI C	View
27	26593963	G328A	LMP1	R S CI C	View
28	26593963	C329T	LMP1	R S CI C	View
29	26593963	A354G	LMP1	R S CI C	View
30	26593963	C356A	LMP1	R S CI C	View
31	26593963	G372A	LMP1	R S CI C	View
32	26593963	G376A	LMP1	R S CI C	View
33	26593963	A39C	LMP1	R S CI C	View
34	26593963	C410A	LMP1	R S CI C	View
35	26593963	T412G	LMP1	R S CI C	View
36	26593963	G426A	LMP1	R S CI C	View
37	26593963	G44C	LMP1	R S CI C	View
38	26593963	G44T	LMP1	R S CI C	View
39	26593963	T50A	LMP1	R S CI C	View
40	26593963	A63C	LMP1	R S CI C	View
41	26593963	T18G	LMP1	R S CI C	View
42	26593963	G41C	LMP1	R S CI C	View
43	26593963	D46N	LMP1	R S CI C	View
44	26593963	E214Q	LMP1	R S CI C	View
45	26593963	F106Y	LMP1	R S CI C	View
46	26593963	G212S	LMP1	R S CI C	View
47	26593963	H213N	LMP1	R S CI C	View
48	26593963	I124V	LMP1	R S CI C	View
49	26593963	I152L	LMP1	R S CI C	View
50	26593963	I63V	LMP1	R S CI C	View
51	26593963	I85L	LMP1	R S CI C	View
52	26593963	L126F	LMP1	R S CI C	View
53	26593963	L151I	LMP1	R S CI C	View
54	26593963	L25I	LMP1	R S CI C	View
55	26593963	L338S	LMP1	R S CI C	View
56	26593963	M129I	LMP1	R S CI C	View
57	26593963	Q322N	LMP1	R S CI C	View
58	26593963	Q334R	LMP1	R S CI C	View
59	26593963	S309N	LMP1	R S CI C	View
60	26593963	S366T	LMP1	R S CI C	View
61	26593963	S57A	LMP1	R S CI C	View
62	30546078	H450P	BPLF1	R S C	View
63	30546078	H481R	BPLF1	R S C	View
64	30546078	T449P	BPLF1	R S C	View
65	30546078	T533A	BPLF1	R S C	View
66	30546078	P482R	BPLF1	R S C	View
67	30546078	S333P	BPLF1	R S C	View
68	30546078	P371Q	BRLF1	R S C	View
69	30546078	357_359 del	EBNA2	R S C	View
70	30546078	T710M	BBLF2/BBLF3	R S C	View
71	30546078	A151E	BOLF1	R S C	View
72	30546078	H2551N	BPLF1	R S C	View
73	30546078	K675E	BBLF4	R S C	View
74	30546078	K675R	BBLF4	R S C	View
75	30546078	P92S	BZLF1	R S C	View
76	30546078	G111E	BZLF1	R S C	View
77	30546078	A206T	BZLF1	R S C	View
78	30546078	H861Q	BALF5	R S C	View
79	30546078	S497G	BNRF1	R S C	View
80	30546078	R2602W	BPLF1	R S C	View
81	30546078	P245Q	EBNA2	R S C	View
82	30546078	R246S	EBNA2	R S C	View
83	30546078	T280N	EBNA2	R S C	View
84	30546078	I151M	EBNA2	R S C	View
85	30546078	H646N	BBLF4	R S C	View
86	30546078	C448F	BFRF2	R S C	View
87	30546078	R2309H	BPLF1	R S C	View
88	30546078	T288S	BRLF1	R S C	View
89	30546078	A797V	EBNA3B	R S C	View
90	30546078	P803T	EBNA3B	R S C	View
91	30546078	Q802H	EBNA3B	R S C	View
92	30546078	A1289T	BNRF1	R S C	View
93	30546078	A399S	EBNA3B	R S C	View
94	30546078	A588P	EBNA3A	R S C	View
95	30546078	F325L	EBNA3A	R S C	View
96	30546078	G373D	EBNA3A	R S C	View
97	30546078	G456R	BNRF1	R S C	View
98	30546078	H464R	EBNA3A	R S C	View
99	30546078	L406P	EBNA3A	R S C	View
100	30546078	I333K	EBNA3A	R S C	View

EBV Overlap Info between Viral Integration Fragments and Cistrome Factors

Click to see statistics heatmap of VIS-Factor Overlap in the human genome of EBV

Click to see histogram of VIS-Factor Overlap by chromosome of EBV

Click to see the overlap count of three factors and EBV intergration fragments on the human chromosomes

Only show 100 info Click here to see all EBV Integration Sites

DVID	Chromosome	Histone Modification	Transcription Factor Binding Site	Chromatin Accessibility	Sum of Overlapped Records	Detail
3000028	chr1	1244	90	51	1385	View
3300196	chr1	529	203	152	884	View
3200036	chr1	379	267	231	877	View
3000059	chr1	159	236	1	396	View
3200005	chr1	331	8	18	357	View
3000064	chr1	125	206	2	333	View
3000083	chr1	158	54	7	219	View
3200038	chr1	104	67	8	179	View
3000101	chr1	14	98	64	176	View
3000106	chr1	9	81	79	169	View
3300098	chr1	107	42		149	View
3000118	chr1	26	47	69	142	View
3000133	chr1	85	31	8	124	View
3000135	chr1	24	29	67	120	View
3000138	chr1	117			117	View
3000152	chr1	105			105	View
3300093	chr1	91			91	View
3000178	chr1	35	38	12	85	View
3000187	chr1	42	38		80	View
3000196	chr1	17	8	51	76	View
3000199	chr1	22	51	2	75	View
3000204	chr1	64	9		73	View
3000214	chr1	45	19	1	65	View
3300032	chr1	30	11	17	58	View
3000228	chr1	56	1		57	View
3000232	chr1	11	8	37	56	View
3000247	chr1	40	11	1	52	View
3300212	chr1	18	6	26	50	View
3300245	chr1	10	29	5	44	View
3000276	chr1	20	23		43	View
3000278	chr1	42	1		43	View
3300117	chr1	27	12	4	43	View
3000280	chr1	30	12		42	View
3000282	chr1	27	5	9	41	View
3000300	chr1	2	35		37	View
3300176	chr1	22	4	11	37	View
3300129	chr1	32	2	2	36	View
3000308	chr1	28	7		35	View
3000330	chr1	23	8		31	View
3000331	chr1	15	2	14	31	View
3000352	chr1	23	6		29	View
3000368	chr1	10	17		27	View
3000380	chr1	24	2		26	View
3000396	chr1	22	1		23	View
3000405	chr1	19	3		22	View
3300054	chr1	2	5	14	21	View
3000440	chr1	14	4		18	View
3000457	chr1	7	4	6	17	View
3000478	chr1	15	1		16	View
3000487	chr1	14	2		16	View
3300170	chr1	10	5		15	View
3000510	chr1	7	7		14	View
3000527	chr1	13			13	View
3300034	chr1	11	2		13	View
3300213	chr1	2	9	2	13	View
3000555	chr1	2	7	2	11	View
3000561	chr1	7	3	1	11	View
3000562	chr1	11			11	View
3000563	chr1	4	7		11	View
3000600	chr1	1	2	6	9	View
3000628	chr1	7	1		8	View
3000629	chr1	5	3		8	View
3000630	chr1	8			8	View
3000631	chr1	5	3		8	View
3000637	chr1	7	1		8	View
3000642	chr1	5	2		7	View
3000643	chr1	5		2	7	View
3100004	chr1	6	1		7	View
3000695	chr1	2	4		6	View
3300008	chr1	1	5		6	View
3000710	chr1	4	1		5	View
3300171	chr1	3	2		5	View
3300248	chr1	1	4		5	View
3000756	chr1	4			4	View
3000765	chr1	1	3		4	View
3000766	chr1	4			4	View
3300275	chr1	2	2		4	View
3000792	chr1	3			3	View
3000803	chr1	3			3	View
3000804	chr1	2	1		3	View
3300246	chr1	3			3	View
3000853	chr1	1	1		2	View
3000854	chr1		2		2	View
3300164	chr1	2			2	View
3300239	chr1	2			2	View
3000918	chr1		1		1	View
3000919	chr1	1			1	View
3000948	chr1		1		1	View
3000949	chr1		1		1	View
3300017	chr1	1			1	View
3300154	chr1		1		1	View
3300237	chr1	1			1	View
3000994	chr1				0	View
3000995	chr1				0	View
3001031	chr1				0	View
3001032	chr1				0	View
3001033	chr1				0	View
3001034	chr1				0	View
3001109	chr1				0	View
3001111	chr1				0	View

EBV Target Gene Info

Click to see correlation between gene expression and proportions of infiltrating immune cells of EBV

Only show 100 info Click here to see all EBV Target Gene

ID	Target gene	Virus	Gene Function	Literature Count	Detail
1	DAPK3	EBV	Suppressor gene	1	View
2	CTNNA2	EBV	Suppressor gene	1	View
3	RB1	EBV	Suppressor gene	1	View
4	CDK2	EBV	Suppressor gene	1	View
5	CBX5	EBV	Suppressor gene	1	View
6	CNTNAP2	EBV	Suppressor gene	1	View
7	WWOX	EBV	Suppressor gene	1	View
8	PFN1	EBV	Suppressor gene	1	View
9	INPP4B	EBV	Suppressor gene	1	View
10	TNFAIP3	EBV	Suppressor gene	1	View
11	BMPR1A	EBV	Suppressor gene	1	View
12	PIWIL2	EBV	Suppressor gene	1	View
13	CADM1	EBV	Suppressor gene	1	View
14	EHD3	EBV	Suppressor gene	1	View
15	EXT1	EBV	Suppressor gene	1	View
16	ROBO1	EBV	Suppressor gene	1	View
17	MTUS1	EBV	Suppressor gene	1	View
18	CFTR	EBV	Suppressor gene	1	View
19	PTPRK	EBV	Suppressor gene	1	View
20	BBC3	EBV	Suppressor gene	1	View
21	CAMTA1	EBV	Suppressor gene	2	View
22	PTPRT	EBV	Suppressor gene	1	View
23	RUNX2	EBV	Suppressor gene	1	View
24	PRDM1	EBV	Suppressor gene	1	View
25	KRIT1	EBV	Suppressor gene	1	View
26	EBF3	EBV	Suppressor gene	1	View
27	NFKB1	EBV	Suppressor gene	8	View
28	SDHB	EBV	Suppressor gene	1	View
29	DDX3X	EBV	Suppressor gene	1	View
30	PLD1	EBV	Suppressor gene	1	View
31	BCL2L11	EBV	Suppressor gene	1	View
32	FAS	EBV	Suppressor gene	2	View
33	FHIT	EBV	Suppressor gene	1	View
34	NGFR	EBV	Suppressor gene	1	View
35	STARD13	EBV	Suppressor gene	1	View
36	POU6F2	EBV	Suppressor gene	1	View
37	CSMD1	EBV	Suppressor gene	1	View
38	TP53	EBV	Suppressor gene	1	View
39	DDX58	EBV	Suppressor gene	1	View
40	MSH2	EBV	Suppressor gene	1	View
41	DKK3	EBV	Suppressor gene	1	View
42	SMARCA4	EBV	Suppressor gene	1	View
43	DPH1	EBV	Suppressor gene	1	View
44	PPARA	EBV	Suppressor gene	1	View
45	PRKAA2	EBV	Suppressor gene	1	View
46	CDCP1	EBV	Suppressor gene	1	View
47	DLEC1	EBV	Suppressor gene	1	View
48	PDS5B	EBV	Suppressor gene	1	View
49	CDH13	EBV	Suppressor gene	1	View
50	DLG1	EBV	Suppressor gene	1	View
51	ESRRB	EBV	Suppressor gene	1	View
52	RASAL2	EBV	Suppressor gene	1	View
53	DENND2B	EBV	Suppressor gene	1	View
54	PEBP1	EBV	Suppressor gene	1	View
55	DMD	EBV	Suppressor gene	2	View
56	FAM172A	EBV	Suppressor gene	1	View
57	KISS1	EBV	Suppressor gene	1	View
58	PCDH9	EBV	Suppressor gene	1	View
59	PRKN	EBV	Suppressor gene	1	View
60	NTRK3	EBV	Oncogene & Suppressor gene	1	View
61	JUP	EBV	Oncogene & Suppressor gene	1	View
62	RUNX1	EBV	Oncogene & Suppressor gene	1	View
63	STAT3	EBV	Oncogene & Suppressor gene	1	View
64	EEF1A1	EBV	Oncogene & Suppressor gene	1	View
65	CDK1	EBV	Oncogene	1	View
66	CDK14	EBV	Oncogene	2	View
67	PTK7	EBV	Oncogene	1	View
68	EWSR1	EBV	Oncogene	1	View
69	AFF1	EBV	Oncogene	1	View
70	NEDD9	EBV	Oncogene	1	View
71	CTNND2	EBV	Oncogene	1	View
72	EGFR	EBV	Oncogene	1	View
73	CTTN	EBV	Oncogene	1	View
74	FOS	EBV	Oncogene	4	View
75	USP4	EBV	Oncogene	1	View
76	ADAM28	EBV	Oncogene	1	View
77	JUN	EBV	Oncogene	4	View
78	LMO4	EBV	Oncogene	1	View
79	MIR99AHG	EBV	Oncogene	1	View
80	CRTC1	EBV	Oncogene	1	View
81	FGF6	EBV	Oncogene	1	View
82	CSNK2A1	EBV	Oncogene	1	View
83	PRKCA	EBV	Oncogene	1	View
84	TBC1D1	EBV	Oncogene	1	View
85	PIK3CA	EBV	Oncogene	1	View
86	PPM1D	EBV	Oncogene	1	View
87	CABIN1	EBV	Oncogene	1	View
88	HAGLR	EBV		1	View
89	NLGN1	EBV		1	View
90	SH3BP2	EBV		1	View
91	TEX2	EBV		1	View
92	GRIK4	EBV		1	View
93	ICAM1	EBV		1	View
94	CPEB2-DT	EBV		1	View
95	MTG1	EBV		1	View
96	NRXN3	EBV		1	View
97	PTGER3	EBV		1	View
98	CTD-2127H91	EBV		1	View
99	LOC105378626	EBV		1	View
100	PPP1R12A	EBV		1	View


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