Overview of EBV Mutation, Integration-Cistrome Factor Overlap and Target gene


Epstein-Barr Virus (EBV), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. The virus is about 122–180 nm in diameter and is composed of a double helix of deoxyribonucleic acid (DNA) which contains about 172,000 base pairs and 85 genes. The DNA is surrounded by a protein nucleocapsid, which is surrounded by a tegument made of protein, which in turn is surrounded by an envelope containing both lipids and surface projections of glycoproteins, which are essential to infection of the host cell.
Size: ~171823 nucleotides [RefSeq: NC_007605]
Encoding: epstein-barr virus genome mainly encodes 86 genes: BXLF2, BZLF1, BGLF4, BARF1, BALF5, RPMS1 and so on
Human Disease: Infection with EBV can lead to Nasopharyngeal carcinoma, B-cell lymphoma, etc. Click here to see all EBV associated human diseases

Click the blue font on the page to view detailed information.
The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale."



EBV Mutation Info
Click here to see all EBV Mutation Sites
IDPMIDMutationGene/Protein/RegionDescriptionDetail
1 28328987 30_bp del
LMP1
R
S
CI
C
View
2 28328987 D150A
LMP1
R
S
CI
C
View
3 28328987 D150G
LMP1
R
S
CI
C
View
4 28328987 F144I
LMP1
R
S
CI
C
View
5 28328987 I124T
LMP1
R
S
CI
C
View
6 28328987 I124V
LMP1
R
S
CI
C
View
7 28328987 I152L
LMP1
R
S
CI
C
View
8 28328987 L151I
LMP1
R
S
CI
C
View
9 26593963 T114C
LMP1
R
S
CI
C
View
10 26593963 G12A
LMP1
R
S
CI
C
View
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EBV Overlap Info between Viral Integration Fragments and Cistrome Factors

Click to see statistics heatmap of VIS-Factor Overlap in the human genome of EBV

Click to see histogram of VIS-Factor Overlap by chromosome of EBV

Click to see the overlap count of three factors and EBV intergration fragments on the human chromosomes

Only show 100 info Click here to see all EBV Integration Sites
DVIDChromosomeHistone ModificationTranscription Factor Binding SiteChromatin AccessibilitySum of Overlapped RecordsDetail
3000028 chr1 1244 90 51 1385 View
3000059 chr1 159 236 1 396 View
3000064 chr1 125 206 2 333 View
3000083 chr1 158 54 7 219 View
3000101 chr1 14 98 64 176 View
3000106 chr1 9 81 79 169 View
3000118 chr1 26 47 69 142 View
3000133 chr1 85 31 8 124 View
3000135 chr1 24 29 67 120 View
3000138 chr1 117 117 View
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EBV Target Gene Info


Click to see correlation between gene expression and proportions of infiltrating immune cells of EBV

Only show 100 info Click here to see all EBV Target Gene
IDTarget geneVirusGene FunctionLiterature Count DescriptionDetail
1 DAPK3 EBV Suppressor gene 1 View
2 CTNNA2 EBV Suppressor gene 1 View
3 RB1 EBV Suppressor gene 1 View
4 CDK2 EBV Suppressor gene 1 View
5 CBX5 EBV Suppressor gene 1 View
6 CNTNAP2 EBV Suppressor gene 1 View
7 WWOX EBV Suppressor gene 1 View
8 PFN1 EBV Suppressor gene 1 View
9 INPP4B EBV Suppressor gene 1 View
10 TNFAIP3 EBV Suppressor gene 1 View
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