Overview of EBV Mutation, Integration-Cistrome Factor Overlap and Target gene

Epstein-Barr Virus (EBV), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans. The virus is about 122–180 nm in diameter and is composed of a double helix of deoxyribonucleic acid (DNA) which contains about 172,000 base pairs and 85 genes. The DNA is surrounded by a protein nucleocapsid, which is surrounded by a tegument made of protein, which in turn is surrounded by an envelope containing both lipids and surface projections of glycoproteins, which are essential to infection of the host cell.
Size: ～171823 nucleotides [RefSeq: NC_007605]
Encoding: epstein-barr virus genome mainly encodes 86 genes: BXLF2, BZLF1, BGLF4, BARF1, BALF5, RPMS1 and so on
Human Disease: Infection with EBV can lead to Nasopharyngeal carcinoma, B-cell lymphoma, etc. Click here to see all EBV associated human diseases

Click the blue font on the page to view detailed information.
The cistrome refers to "the set of cis-acting targets of a trans-acting factor on a genome-wide scale."

EBV Mutation Info

Click here to see all EBV Mutation Sites

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	26593963	A184T	LMP1	R S CI C	View
2	26593963	C199T	LMP1	R S CI C	View
3	26593963	C207T	LMP1	R S CI C	View
4	26593963	G227A	LMP1	R S CI C	View
5	26593963	G233A	LMP1	R S CI C	View
6	26593963	G234T	LMP1	R S CI C	View
7	26593963	A238G	LMP1	R S CI C	View
8	26593963	G240A	LMP1	R S CI C	View
9	26593963	T242C	LMP1	R S CI C	View
10	26593963	C272G	LMP1	R S CI C	View
11	26593963	G284T	LMP1	R S CI C	View
12	26593963	A286G	LMP1	R S CI C	View
13	26593963	A314G	LMP1	R S CI C	View
14	26593963	C315T	LMP1	R S CI C	View
15	26593963	G328A	LMP1	R S CI C	View
16	26593963	C329T	LMP1	R S CI C	View
17	26593963	A354G	LMP1	R S CI C	View
18	26593963	C356A	LMP1	R S CI C	View
19	26593963	G372A	LMP1	R S CI C	View
20	26593963	G376A	LMP1	R S CI C	View
21	26593963	A39C	LMP1	R S CI C	View
22	26593963	C410A	LMP1	R S CI C	View
23	26593963	T412G	LMP1	R S CI C	View
24	26593963	G426A	LMP1	R S CI C	View
25	26593963	G44C	LMP1	R S CI C	View
26	26593963	G44T	LMP1	R S CI C	View
27	26593963	T50A	LMP1	R S CI C	View
28	26593963	A63C	LMP1	R S CI C	View
29	26593963	T18G	LMP1	R S CI C	View
30	26593963	G41C	LMP1	R S CI C	View
31	26593963	D46N	LMP1	R S CI C	View
32	26593963	E214Q	LMP1	R S CI C	View
33	26593963	F106Y	LMP1	R S CI C	View
34	26593963	G212S	LMP1	R S CI C	View
35	26593963	H213N	LMP1	R S CI C	View
36	26593963	I124V	LMP1	R S CI C	View
37	26593963	I152L	LMP1	R S CI C	View
38	26593963	I63V	LMP1	R S CI C	View
39	26593963	I85L	LMP1	R S CI C	View
40	26593963	L126F	LMP1	R S CI C	View
41	26593963	L151I	LMP1	R S CI C	View
42	26593963	L25I	LMP1	R S CI C	View
43	26593963	L338S	LMP1	R S CI C	View
44	26593963	M129I	LMP1	R S CI C	View
45	26593963	Q322N	LMP1	R S CI C	View
46	26593963	Q334R	LMP1	R S CI C	View
47	26593963	S309N	LMP1	R S CI C	View
48	26593963	S366T	LMP1	R S CI C	View
49	26593963	S57A	LMP1	R S CI C	View
50	26593963	T172C	LMP1	R S CI C	View
51	26593963	C158T	LMP1	R S CI C	View
52	26593963	G12A	LMP1	R S CI C	View
53	26593963	T114C	LMP1	R S CI C	View
54	28328987	L151I	LMP1	R S CI C	View
55	28328987	I152L	LMP1	R S CI C	View
56	28328987	I124V	LMP1	R S CI C	View
57	28328987	I124T	LMP1	R S CI C	View
58	28328987	F144I	LMP1	R S CI C	View
59	28328987	D150G	LMP1	R S CI C	View
60	28328987	D150A	LMP1	R S CI C	View
61	28328987	30_bp del	LMP1	R S CI C	View
62	30546078	K424T	EBNA3B	R S C	View
63	30111570	G27S	EBNA1	R S C	View
64	30111570	G18E	EBNA1	R S C	View
65	30111570	G113E	EBNA3	R S C	View
66	30111570	E24D	EBNA1	R S C	View
67	30111570	E16Q	EBNA1	R S C	View
68	30111570	C114R	EBNA3	R S C	View
69	30111570	A38S	EBNA3	R S C	View
70	30111570	G155391A	RPMS1	R S C	View
71	30111570	C155389T	RPMS1	R S C	View
72	30111570	T85A	EBNA1	R S C	View
73	30111570	Q92K	EBNA3	R S C	View
74	30111570	T20S	EBNA1	R S C	View
75	30111570	T585I	EBNA1	R S C	View
76	30546078	A241T	LF1	R S C	View
77	30546078	G234E	LF1	R S C	View
78	30546078	V26G	BFRF2	R S C	View
79	30546078	F332V	BFRF1	R S C	View
80	30546078	R413G	EBNA2	R S C	View
81	30546078	E326Q	LMP1	R S C	View
82	30546078	R462Q	BFRF2	R S C	View
83	30546078	T170M	BBLF2/BBLF3	R S C	View
84	30546078	S654P	BBLF2/BBLF3	R S C	View
85	30546078	H614R	BBLF2/BBLF3	R S C	View
86	30546078	G696R	BNRF1	R S C	View
87	30546078	A281T	BFLF2	R S C	View
88	30546078	D402N	EBNA3B	R S C	View
89	30546078	T696I	EBNA3B	R S C	View
90	30546078	T581N	EBNA3B	R S C	View
91	30546078	G36E	EBNA3B	R S C	View
92	30546078	T357A	EBNA3A	R S C	View
93	30546078	A427S	BRRF2	R S C	View
94	30546078	Q3036E	BPLF1	R S C	View
95	30546078	R125S	BGLF1	R S C	View
96	30546078	C229G	LMP2	R S C	View
97	30546078	A1236T	BOLF1	R S C	View
98	30546078	M195T	EBNA2	R S C	View
99	30546078	Q489K	BRLF1	R S C	View
100	30546078	P2765S	BPLF1	R S C	View

EBV Overlap Info between Viral Integration Fragments and Cistrome Factors

Click to see statistics heatmap of VIS-Factor Overlap in the human genome of EBV

Click to see histogram of VIS-Factor Overlap by chromosome of EBV

Click to see the overlap count of three factors and EBV intergration fragments on the human chromosomes

Only show 100 info Click here to see all EBV Integration Sites

DVID	Chromosome	Histone Modification	Transcription Factor Binding Site	Chromatin Accessibility	Sum of Overlapped Records	Detail
3000028	chr1	1244	90	51	1385	View
3300196	chr1	529	203	152	884	View
3200036	chr1	379	267	231	877	View
3000059	chr1	159	236	1	396	View
3200005	chr1	331	8	18	357	View
3000064	chr1	125	206	2	333	View
3000083	chr1	158	54	7	219	View
3200038	chr1	104	67	8	179	View
3000101	chr1	14	98	64	176	View
3000106	chr1	9	81	79	169	View
3300098	chr1	107	42		149	View
3000118	chr1	26	47	69	142	View
3000133	chr1	85	31	8	124	View
3000135	chr1	24	29	67	120	View
3000138	chr1	117			117	View
3000152	chr1	105			105	View
3300093	chr1	91			91	View
3000178	chr1	35	38	12	85	View
3000187	chr1	42	38		80	View
3000196	chr1	17	8	51	76	View
3000199	chr1	22	51	2	75	View
3000204	chr1	64	9		73	View
3000214	chr1	45	19	1	65	View
3300032	chr1	30	11	17	58	View
3000228	chr1	56	1		57	View
3000232	chr1	11	8	37	56	View
3000247	chr1	40	11	1	52	View
3300212	chr1	18	6	26	50	View
3300245	chr1	10	29	5	44	View
3000276	chr1	20	23		43	View
3000278	chr1	42	1		43	View
3300117	chr1	27	12	4	43	View
3000280	chr1	30	12		42	View
3000282	chr1	27	5	9	41	View
3000300	chr1	2	35		37	View
3300176	chr1	22	4	11	37	View
3300129	chr1	32	2	2	36	View
3000308	chr1	28	7		35	View
3000330	chr1	23	8		31	View
3000331	chr1	15	2	14	31	View
3000352	chr1	23	6		29	View
3000368	chr1	10	17		27	View
3000380	chr1	24	2		26	View
3000396	chr1	22	1		23	View
3000405	chr1	19	3		22	View
3300054	chr1	2	5	14	21	View
3000440	chr1	14	4		18	View
3000457	chr1	7	4	6	17	View
3000478	chr1	15	1		16	View
3000487	chr1	14	2		16	View
3300170	chr1	10	5		15	View
3000510	chr1	7	7		14	View
3000527	chr1	13			13	View
3300034	chr1	11	2		13	View
3300213	chr1	2	9	2	13	View
3000555	chr1	2	7	2	11	View
3000561	chr1	7	3	1	11	View
3000562	chr1	11			11	View
3000563	chr1	4	7		11	View
3000600	chr1	1	2	6	9	View
3000628	chr1	7	1		8	View
3000629	chr1	5	3		8	View
3000630	chr1	8			8	View
3000631	chr1	5	3		8	View
3000637	chr1	7	1		8	View
3000642	chr1	5	2		7	View
3000643	chr1	5		2	7	View
3100004	chr1	6	1		7	View
3000695	chr1	2	4		6	View
3300008	chr1	1	5		6	View
3000710	chr1	4	1		5	View
3300171	chr1	3	2		5	View
3300248	chr1	1	4		5	View
3000756	chr1	4			4	View
3000765	chr1	1	3		4	View
3000766	chr1	4			4	View
3300275	chr1	2	2		4	View
3000792	chr1	3			3	View
3000803	chr1	3			3	View
3000804	chr1	2	1		3	View
3300246	chr1	3			3	View
3000853	chr1	1	1		2	View
3000854	chr1		2		2	View
3300164	chr1	2			2	View
3300239	chr1	2			2	View
3000918	chr1		1		1	View
3000919	chr1	1			1	View
3000948	chr1		1		1	View
3000949	chr1		1		1	View
3300017	chr1	1			1	View
3300154	chr1		1		1	View
3300237	chr1	1			1	View
3000994	chr1				0	View
3000995	chr1				0	View
3001031	chr1				0	View
3001032	chr1				0	View
3001033	chr1				0	View
3001034	chr1				0	View
3001109	chr1				0	View
3001111	chr1				0	View

EBV Target Gene Info

Click to see correlation between gene expression and proportions of infiltrating immune cells of EBV

Only show 100 info Click here to see all EBV Target Gene

ID	Target gene	Virus	Gene Function	Literature Count	Detail
1	CNTNAP2	EBV	Suppressor gene	1	View
2	SMARCA4	EBV	Suppressor gene	1	View
3	INPP4B	EBV	Suppressor gene	1	View
4	KISS1	EBV	Suppressor gene	1	View
5	CFTR	EBV	Suppressor gene	1	View
6	PCDH9	EBV	Suppressor gene	1	View
7	STARD13	EBV	Suppressor gene	1	View
8	CDK2	EBV	Suppressor gene	1	View
9	KRIT1	EBV	Suppressor gene	1	View
10	CSMD1	EBV	Suppressor gene	1	View
11	CDH13	EBV	Suppressor gene	1	View
12	CDCP1	EBV	Suppressor gene	1	View
13	NGFR	EBV	Suppressor gene	1	View
14	NFKB1	EBV	Suppressor gene	8	View
15	CTNNA2	EBV	Suppressor gene	1	View
16	PDS5B	EBV	Suppressor gene	1	View
17	PEBP1	EBV	Suppressor gene	1	View
18	DAPK3	EBV	Suppressor gene	1	View
19	PFN1	EBV	Suppressor gene	1	View
20	CBX5	EBV	Suppressor gene	1	View
21	MTUS1	EBV	Suppressor gene	1	View
22	DDX3X	EBV	Suppressor gene	1	View
23	DDX58	EBV	Suppressor gene	1	View
24	CAMTA1	EBV	Suppressor gene	2	View
25	DENND2B	EBV	Suppressor gene	1	View
26	CADM1	EBV	Suppressor gene	1	View
27	SDHB	EBV	Suppressor gene	1	View
28	MSH2	EBV	Suppressor gene	1	View
29	DKK3	EBV	Suppressor gene	1	View
30	DLEC1	EBV	Suppressor gene	1	View
31	DLG1	EBV	Suppressor gene	1	View
32	PIN1	EBV	Suppressor gene	1	View
33	DMD	EBV	Suppressor gene	2	View
34	TNFAIP3	EBV	Suppressor gene	1	View
35	BMPR1A	EBV	Suppressor gene	1	View
36	PIWIL2	EBV	Suppressor gene	1	View
37	TP53	EBV	Suppressor gene	1	View
38	BCL2L11	EBV	Suppressor gene	1	View
39	PLD1	EBV	Suppressor gene	1	View
40	BBC3	EBV	Suppressor gene	1	View
41	DPH1	EBV	Suppressor gene	1	View
42	RUNX2	EBV	Suppressor gene	1	View
43	EBF3	EBV	Suppressor gene	1	View
44	FAS	EBV	Suppressor gene	2	View
45	RASAL2	EBV	Suppressor gene	1	View
46	POU6F2	EBV	Suppressor gene	1	View
47	EHD3	EBV	Suppressor gene	1	View
48	PPARA	EBV	Suppressor gene	1	View
49	PTPRT	EBV	Suppressor gene	1	View
50	ROBO1	EBV	Suppressor gene	1	View
51	FAM172A	EBV	Suppressor gene	1	View
52	WWOX	EBV	Suppressor gene	1	View
53	RB1	EBV	Suppressor gene	1	View
54	PRDM1	EBV	Suppressor gene	1	View
55	FHIT	EBV	Suppressor gene	1	View
56	PRKN	EBV	Suppressor gene	1	View
57	EXT1	EBV	Suppressor gene	1	View
58	ESRRB	EBV	Suppressor gene	1	View
59	PRKAA2	EBV	Suppressor gene	1	View
60	EEF1A1	EBV	Oncogene & Suppressor gene	1	View
61	JUP	EBV	Oncogene & Suppressor gene	1	View
62	RUNX1	EBV	Oncogene & Suppressor gene	1	View
63	NTRK3	EBV	Oncogene & Suppressor gene	1	View
64	STAT3	EBV	Oncogene & Suppressor gene	1	View
65	JUN	EBV	Oncogene	4	View
66	CSNK2A1	EBV	Oncogene	1	View
67	CDK1	EBV	Oncogene	1	View
68	AFF1	EBV	Oncogene	1	View
69	NEDD9	EBV	Oncogene	1	View
70	CTNND2	EBV	Oncogene	1	View
71	CTTN	EBV	Oncogene	1	View
72	TBC1D1	EBV	Oncogene	1	View
73	CDK14	EBV	Oncogene	2	View
74	ADAM28	EBV	Oncogene	1	View
75	PTK7	EBV	Oncogene	1	View
76	CRTC1	EBV	Oncogene	1	View
77	EWSR1	EBV	Oncogene	1	View
78	PRKCA	EBV	Oncogene	1	View
79	CABIN1	EBV	Oncogene	1	View
80	FGF6	EBV	Oncogene	1	View
81	USP4	EBV	Oncogene	1	View
82	PIK3CA	EBV	Oncogene	1	View
83	MIR99AHG	EBV	Oncogene	1	View
84	EGFR	EBV	Oncogene	1	View
85	LMO4	EBV	Oncogene	1	View
86	PPM1D	EBV	Oncogene	1	View
87	FOS	EBV	Oncogene	4	View
88	PEX11G	EBV		1	View
89	PTPDC1	EBV		1	View
90	PDE3A	EBV		1	View
91	PAGE4	EBV		1	View
92	PTGFRN	EBV		1	View
93	NSRP1	EBV		1	View
94	PAK2	EBV		1	View
95	PAM	EBV		1	View
96	PTPRG	EBV		1	View
97	PCBP1	EBV		1	View
98	PCDH11Y	EBV		1	View
99	PDE10A	EBV		1	View
100	PCNX4	EBV		1	View


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