|
Mutation Information
|
Mutation Site
|
T118K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Immune Escape
|
Y |
|
Relevant Drug
|
rituximab;lamivudine (LAM) |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
22138369
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
The Journal of infection |
|
Title
|
Late hepatitis B virus reactivation after lamivudine prophylaxis interruption in an anti-HBs-positive and anti-HBc-negative patient treated with rituximab-containing therapy. |
|
Author
|
Ceccarelli L,Salpini R,Sarmati L,Svicher V,Bertoli A,Sordillo P,Ricciardi A,Perno CF,Andreoni M,Sarrecchia C |
|
Evidence
|
The patient carried a hepatitis B genotype D virus harbouring a single immune escape mutation, sT118K.
|
|
|
HBV Mutation Detail Information