HBV Target gene Detail Information

> TP53 Gene Search Result


Gene Information
Gene Name TP53
Gene ID 7157
Gene Full Name tumor protein p53
Gene Alias P53; BCC7; LFS1; BMFS5; TRP53
Transcripts ENSG00000141510
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters
Gene Function Suppressor gene
Uniport_ID P04637
HGNC ID HGNC:11998
VEGA ID OTTHUMG00000162125
OMIM ID 191170
String ID 9606.ENSP00000269305
Drugbank ID BE0003380
PharmGKB ID PA36679
FDA Approved Drug Venetoclax
Target gene [TP53] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 20962085 F141L
PreS2
G
R
C
View
2 26706415 A10R
X
G
S
C
View
3 19099581 A1762T
BCP
G
C
View
4 22962577 C1653T
C Promoter
G
C
View
5 31565220 I127L
X
R
C
View
6 31565220 I127N
X
R
C
View
7 31565220 I127S
X
R
C
View
8 31565220 I127T
X
R
C
View
9 31565220 K130M
X
R
C
View
10 31565220 R87G
X
R
C
View
11 31565220 R87W
X
R
C
View
12 31565220 V131I
X
R
C
View
13 21438026 A1762T
BCP
G
View
14 21438026 G1764A
BCP
G
View
15 21438026 K130M
X
G
View
16 21438026 V131I
X
G
View
17 25567052 G1764A
BCP
G
View
18 25567052 T1753A
BCP
G
View
19 29479565 A2189C
C
C
View
20 29479565 G1764A
BCP
C
View
21 17622616 P101S
X
View

Target gene [TP53] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005089 chr17 54 7 61 View
1005178 chr17 55 4 59 View
1005210 chr17 54 4 58 View
1401149 chr17 54 4 58 View
1401150 chr17 55 4 59 View
1401151 chr17 54 7 61 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).