|
Mutation Information
|
Mutation Site
|
G145R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
B;C |
|
Viral Reference
|
M54923
|
|
Immune Escape
|
Y |
|
Country
|
Indonesia |
Literature Information
|
PubMed PMID
|
27624502
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Hepatology international |
|
Title
|
Hepatitis B virus infection in children of HBV-related chronic liver disease patients: a study of intra-familial HBV transmission. |
|
Author
|
Gunardi H,Iskandar MY,Turyadi,Ie SI,Dwipoerwantoro PG,Gani RA,Muljono DH |
|
Evidence
|
Recognized mutations associated with HBsAg detection and/or vaccination failure, T140I, T143S/M, G145R, and Y161F, were identified in 20 subjects; while mutations linked to HBeAg-defective variants, PC G1896A and BCP A1762T/G1764A, were found in 7 and 11 subjects, respectively.
|
|
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HBV Mutation Detail Information