Mutation Information
Mutation Site
|
A184T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
LMP1 |
Viral Reference
|
NC007605.1
|
Country
|
Ghana;Brazil;Argentina |
Literature Information
PubMed PMID
|
26593963
|
Clinical information
|
Yes
|
Disease
|
Burkitt lymphoma
|
Published Year
|
2015 |
Journal
|
Scientific reports |
Title
|
Epstein-Barr virus from Burkitt Lymphoma biopsies from Africa and South America share novel LMP-1 promoter and gene variations. |
Author
|
Lei H,Li T,Li B,Tsai S,Biggar RJ,Nkrumah F,Neequaye J,Gutierrez M,Epelman S,Mbulaiteye SM,Bhatia K,Lo SC |
Evidence
|
The 12 novel nucleotide variations in the LMP-1 promoter were: G-426A, T-412G, C-410A, G-376A, A-354G, G-227A, A-184T, T-172C, T-50A, A-39C, G-12A, and T+18G. All 12 nucleotide variations imputed in the LMP-1 promoter were found in the EBV from Raji cell line.
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