EBV Mutation Detail Information

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Mutation Information

Mutation Site	T172C
Mutation Type	Nucleotide level
Gene/Protein/Region Type	LMP1
Viral Reference	NC007605.1
Country	Ghana;Brazil;Argentina

Literature Information

PubMed PMID	26593963
Clinical information	Yes
Disease	Burkitt lymphoma
Published Year	2015
Journal	Scientific reports
Title	Epstein-Barr virus from Burkitt Lymphoma biopsies from Africa and South America share novel LMP-1 promoter and gene variations.
Author	Lei H,Li T,Li B,Tsai S,Biggar RJ,Nkrumah F,Neequaye J,Gutierrez M,Epelman S,Mbulaiteye SM,Bhatia K,Lo SC
Evidence	The 12 novel nucleotide variations in the LMP-1 promoter were: G-426A, T-412G, C-410A, G-376A, A-354G, G-227A, A-184T, T-172C, T-50A, A-39C, G-12A, and T+18G. All 12 nucleotide variations imputed in the LMP-1 promoter were found in the EBV from Raji cell line.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation