HTLV1 Mutation Detail Information

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Mutation Information
Mutation Site C7920T
Mutation Type Nucleotide level
Gene/Protein/Region Type Tax
Viral Reference J02029.1
Country Brazil
Literature Information
PubMed PMID 17067264
Disease Adult T cell leukemia/lymphoma; HTLV-1 associated myelopathy/tropical spastic paraparesis
Published Year 2006
Journal AIDS research and human retroviruses
Title Distribution of human T cell lymphotropic virus type 1 (HTLV-1) subtypes in Brazil: genetic characterization of LTR and tax region.
Author Kashima S,Alcantara LC,Takayanagui OM,Cunha MA,Castro BG,Pombo-de-Oliveira MS,Zago MA,Covas DT
Evidence Five specific nucleotide substitutions, C7401T, T7914C, C7920T, C7982T, and G8231A, were highly conserved among the Brazilian isolates (79.6%), with a frequency ranging from 81.6% to 100% in the sample group and from 18.4% to 24.1% in the prototypes used, suggesting the existence of a molecular signature.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation